Interdisciplinary Centre Luxembourg Centre for Systems Biomedicine (LCSB)

Aquatic Platform

The Aquatic Platform consists of a modern, semi-automated installation that provides zebrafish housing, husbandry, and experimental services to support biomedical research and teaching activities. Currently, the facility can house up to 30.000 adult zebrafish, offering robotic feeding, maintenance of constant micro-environmental parameters (e.g. pH, temperature and conductivity), and semi-automated cleaning systems that ensure excellent conditions for research quality and animal welfare.

In well-equipped laboratories the Aquatic Platform offers and supports the generation and characterisation of zebrafish disease models using morpholino antisense technology and CRISPR/Cas9 mutagenesis, as well as reporter lines and pharmacological models. Moreover, the platform offers the performance of small molecule screens in zebrafish disease models and reporter lines, as well as toxicity screens for drug safety assessment.

With the services of the Aquatic Platform researchers at the LCSB are using zebrafish as a vertebrate animal model to study various human diseases, particularly of the central nervous system.

Email: LCSB-aquatics [at] uni.lu