Research Group Enzymology & Metabolism

Key Publications

  1. Heins-Marroquin U.; Singh, R.R.; Gavotto, F.; Patraskaki, M.; Schymanski, E.L.; Linster, C.L et al. (2024) CLN3 deficiency leads to neurological and metabolic perturbations during early development, Life Science Alliance, Vol. 7 DOI:
  2. Van Bergen, N.J.; Paczia N.; Becker-Kettern J.; Conrotte J.F.; Linster, C.L et al. (2018) NAD(P)HX dehydratase (NAXD) deficiency: a novel neurodegenerative disorder exacerbated by febrile illnesses, Brain, Vol 142 DOI:
  3. Favilli, L.; Griffith, C.; Schymanski, E.L.; Linster, C.L. (2023) High-throughput Saccharomyces cerevisiae cultivation method for credentialing-based untargeted metabolomics, Analytical and Bioanalytical Chemistry, 415, 3415-3434. DOI: 10.1007/s00216-023-04724-5
  4. Gavriil, M.; Proietto, M.; Paczia, N.; Linster, C.L et al. (2023) 2-Hydroxyglutarate modulates histone methylation at specific loci and alters gene expression via Rph1 inhibition, Life Science Alliance, Vol. 7 DOI:
  5. Griffith, C.; Walvekar, A.; Linster, C.L (2021) Approaches for completing metabolic networks through metabolite damage and repair discovery, ScienceDirect, Vol.28 DOI:
  6. Heins-Marroquin, U.; Jung P.P.; Linster, C.L. et al. (2019) Phenotypic assays in yeast and zebrafish reveal drugs that rescue ATP13A2 deficiency, Brain Communications, Vol. 1 DOI:
  7. Soliman, R.; Conrotte, J.F. ; Linster, C.L. et al. (2021) l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain, Frontiers, Vol. 11 DOI: