Research in the field of Molecular Systems Biology
Our research group is focused on the field of molecular systems biology, applying approaches like epigenomics and transcriptomics. We employ cutting-edge data analysis and integration techniques, including statistical methods, machine learning, and network-based approaches, to unravel the complexities of biological systems in health and disease.
Analysis of disease-specific molecular networks
Omics approaches allow for a deep characterization of network alterations in diseases. Data integration and network modelling approaches allow to extract knowledge from such data and to understand key properties of the biological systems under investigation. We focus on metabolism, gene regulation, and epigenetic mechanisms that determine cell identity and its alterations in cancer, in inherited metabolic disorders, and in neurological disorders. The analysis methods are also applied to other biological processes and to clinical data of patient cohorts.
Head of Group
