Prof. Niclou was trained in biology at the University of Fribourg in Switzerland and earned a PhD in cellular biology at the Friedrich-Miescher Institute and University of Basel, Switzerland. She trained as postdoctoral fellow in the Neuroscience Department of the Medical School at the University of Pennsylvania , Philadelphia (US) and at the Netherlands Institute of Neuroscience in Amsterdam (Netherlands), before she joined in 2005 the Luxembourg Institute of Health (LIH), where she set up and led a research team in neuro-oncology. Her research interests focus on the biology of malignant brain tumours, specifically addressing the molecular heterogeneity, the plasticity and the metabolism of malignant gliomas. Her lab has made major contributions to the establishment and characterization of advanced preclinical models of glioma, which are sought-after by numerous academic and private partners worldwide. In 2014, she was nominated adjunct professor at the University of Bergen in Norway, where she maintained a highly productive research cooperation. From 2019-2023, she was Director of the Department of Cancer Research at LIH, with a strong involvement in people management, institutional strategies and policies.
Prof. Niclou has been the recipient of multiple research grants and was granted two large multi-institutional doctoral training units in cancer biology in close partnership with the University of Luxembourg. In 2007 Prof. Niclou received the FNR ‘Best Publication Award’ and in 2021, the FNR Award for ‘Outstanding Scientific Achievements’. She served on the Executive Board of EANO ( European Association for Neuro-Oncology ) and of the EANO Educational Committee. She is also part of the EORTC Brain Tumor Group and of the ESMO Faculty on CNS tumors. She serves on the editorial board of Neuro-Oncology and is associate editor of the sister journal Neuro-Oncology Advances . She is regularly invited to present at international conferences, and sollicited for international evaluation committees and grant review panels. At the national level, she has been the President of the Laboratoire national de santé (2015-2019) and is supervising the research agenda of the National Cancer Plan under the auspices of the Luxembourg Ministry of Health.
Prof. Niclou is of Luxembourgish nationality and is fluent in English, French, German, Dutch and Luxembourgish.