ExpoBiome - Deciphering the impact of exposures from the gut microbiome-derived molecular complex in human health and disease - LCSB

Gut microbiome molecular complex in human health and disease

The project at a glance

Start date:

01 Nov 2020
Duration in months:

60
Funding:

European Research Council (ERC)
Principal Investigator(s):

Paul Wilmes

Jochen Schneider

Patrick May

Brit Mollenhauer (PI) (external)

Andreas Michalsen (PI) (external)

Robert L. Hettich (external)

About

The human gut microbiome is a complex ecosystem with essential contributions to human physiology. Microbiome changes are implicated in several chronic diseases characterised by inflammation, including neurodegenerative and autoimmune diseases. Microbiome-derived molecules including nucleic acids, polypeptides and metabolites have not been studied systematically.

The EU-funded ExpoBiome project aims to integrate high-resolution methodologies to study these molecular complexes and their impact on the human immune system in the context of health and disease. By facilitating the elucidation of currently unknown microbiome-derived molecules, the project will identify new genes, proteins, metabolites and essential pathways for the development of potential diagnostics and therapeutic applications.

This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 863664).

CORDIS – European Commission