Research Group Computational Biology

Tools

Cell Engineering

  • SinCMat

    Single-cell based method for predicting functional maturation transcription factors.

  • SeeSawPred

    Web application for predicting cell-fate determinants in binary cell differentiation.

  • TransSinW

    Single-cell RNA-seq based web application to guide cell conversion experiments.

  • IRENE

    Computer-guided design tool for efficient cellular conversion using multi-OMIC data.

General Tools

  • ChemPert

    Web and database to predict transcriptional responses of non-cancer cells to various perturbagens

  • SigHotSpotter

    Web application for identifying signaling molecules by integrating signaling and transcriptional networks

  • InterCom

    Mechanistic computational model integrating extracellular binding events with intracellular signaling cascades.

  • GRNOptR

    Gene Regulatory Network Inference tool using booleanized transcriptomic data and Prior Knowledge Networks.

Ageing and Rejuvenation

  • SINGULAR

    Cell rejuvenation atlas providing unified system biology analysis of diverse rejuvenation strategies across multiple organs at single-cell resolution.

  • MultiTIMER

    Multi-tissue aging clock measuring biological age of cells from their transcriptional profiles by evaluating key cellular processes. 

All images were created using BioRender.com