SAVE THE DATE !
Wednesday, October 12, 2022 at 16:00
Macromolecules and Microsystems in Biology and Medicine Laboratory,
Institut Curie – Centre de Recherche, UMR 168
Institut Pierre Gilles de Gennes pour la Microfluidique (IPGG) Paris, France
Over the past few decades, microfluidics has emerged as an extensive and multidisciplinary area of research within the domain of fluid dynamics. The rise in technological advancements especially in the field of electronics and instrumentation has resulted in the development of microfluidics based biomedical devices and techniques for diagnosis, vital monitoring, support systems, and therapeutic screening. Microfluidics comes handy due to its inherent advantages in sensing, sample requirements, time of detection and the affordability to the masses. In the light of these developments in the field of microfluidics with potential applications in areas ranging from soft matter physics to global healthcare, my research was focused on experimental and theoretical aspects of fluid flows in deformable microchannels that mimic the human vasculature. The experimental results, corroborated with theoretical analysis have demonstrated the intricate relationship of the wall deformation and the pressure drop across a deformable microchannel. Later, it was extended to time varying flows and flows of red blood cells in hydrogel based deformable microchannels. Another aspect that would be discussed is the wetting of droplets laden with microparticles and bacteria on highly repellent (superhydrophobic) surfaces. Further in the fight against cancer, commonly followed microfluidics-based approaches for cancer drug screening are complicated and expensive, that warrant high-end equipment and sophisticated fabrication techniques. We propose a low-cost drug screening and viability testing platform with minimal fabrication requirements. A novel method of tumoroid generation inside a microfluidic environment is introduced that exploits pure hydrodynamic and interfacial effects for the screening of chemotherapy drugs.
Speaker bio: https://www.linkedin.com/in/kiran-raj-m-73b83562/