{"id":12572,"date":"2025-03-05T17:23:13","date_gmt":"2025-03-05T16:23:13","guid":{"rendered":"https:\/\/www.uni.lu\/research-en\/?post_type=research-projects&#038;p=12572"},"modified":"2025-07-15T10:42:11","modified_gmt":"2025-07-15T08:42:11","slug":"kdrecell-leveraging-knowledge-enhanced-deep-learning-models-for-cell-reprogramming","status":"publish","type":"research-projects","link":"https:\/\/www.uni.lu\/research-en\/research-projects\/kdrecell-leveraging-knowledge-enhanced-deep-learning-models-for-cell-reprogramming\/","title":{"rendered":"KDReCell: Leveraging Knowledge-Enhanced Deep Learning Models for Cell Reprogramming"},"content":{"rendered":"\n<section class=\"py-0 wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\">\n<section class=\"section no-padding-y wp-block-unilux-blocks-hero\">\n    <div class=\"hero hero--2  \">\n        \n<header class=\"wp-block-unilux-blocks-wrapper hero__header\">\n<div class=\"wp-block-unilux-blocks-wrapper hero__container\">\n<span class=\"hero__title__subject wp-block-unilux-blocks-plain-text\"><\/span>\n\n\n<h1 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"kdrecell-leveraging-knowledge-enhanced-deep-learning-models-for-cell-reprogramming\"\n    >\nKDReCell: Leveraging Knowledge-Enhanced Deep Learning Models for Cell Reprogramming<\/h1>\n<\/div>\n<\/header>\n<figure class=\"wp-block-dev4-reusable-blocks-image hero__visual object-fit--cover\">\n    \n<img decoding=\"async\" class=\"wp-block-image unilux-custom-image-block\"\n                alt=\"\"\n            src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/8\/2025\/03\/steve-johnson-DSN0RxpDRNI-unsplash-scaled.jpg\"\n                srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/8\/2025\/03\/steve-johnson-DSN0RxpDRNI-unsplash-300x258.jpg 300w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/8\/2025\/03\/steve-johnson-DSN0RxpDRNI-unsplash-1024x881.jpg 1024w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/8\/2025\/03\/steve-johnson-DSN0RxpDRNI-unsplash-768x661.jpg 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/8\/2025\/03\/steve-johnson-DSN0RxpDRNI-unsplash-1536x1321.jpg 1536w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/8\/2025\/03\/steve-johnson-DSN0RxpDRNI-unsplash-2048x1762.jpg 2048w\"\n                style=\"object-position: 60.00% 49.00%; font-family: &quot;object-fit: cover; object-position: 60.00% 49.00%;&quot;; aspect-ratio: 16\/9; object-fit: cover; width: 100%;\"\n        loading=\"lazy\"\n\/>    <\/figure>\n<div class=\"wp-block-unilux-blocks-wrapper hero__body\">\n<div class=\"wp-block-unilux-blocks-wrapper hero__container\">\n<p class=\"wp-block-unilux-blocks-plain-text\"><\/p>\n\n\n<ul class=\"wp-block-unilux-blocks-custom-buttons btn-list\">\n\n<\/ul>\n<\/div>\n<\/div>\n    <\/div>\n<\/section><\/div><\/section>\n\n\n\n<section class=\"py-0 wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\">\n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"the-project-at-a-glance\"\n    >\n<br>The project at a glance<\/h2>\n\n\n<div class=\"icon-info-wrapper\">\n    <ul class=\"wp-block-unilux-blocks-icon-info\">\n        <li class=\"wp-block-unilux-blocks-icon-info-item\">\n    \n<div class=\"wp-block-unilux-blocks-wrapper icon-info\">\n<div class=\"icon--primary icon--secondary-2  wp-block-unilux-blocks-icon-picker\">\n    <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--duration \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--duration\"><\/use><\/svg><\/div>\n\n\n<p class=\"has-1-125-rem-font-size\">Start date:<br><strong>01 March 2025<\/strong><\/p>\n<\/div>\n<\/li>\n<li class=\"wp-block-unilux-blocks-icon-info-item\">\n    \n<div class=\"wp-block-unilux-blocks-wrapper icon-info\">\n<div class=\"icon--primary icon--secondary-2  wp-block-unilux-blocks-icon-picker\">\n    <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--format \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--format\"><\/use><\/svg><\/div>\n\n\n<p class=\"has-1-125-rem-font-size\">Duration in months:<br><strong>36<\/strong><br><\/p>\n<\/div>\n<\/li>\n<li class=\"wp-block-unilux-blocks-icon-info-item\">\n    \n<div class=\"wp-block-unilux-blocks-wrapper icon-info\">\n<div class=\"icon--primary icon--secondary-2  wp-block-unilux-blocks-icon-picker\">\n    <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--funding \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--funding\"><\/use><\/svg><\/div>\n\n\n<p class=\"has-1-125-rem-font-size\">Funding:<br><strong>IAS Luxembourg \/ European Commission<\/strong><\/p>\n<\/div>\n<\/li>\n<li class=\"wp-block-unilux-blocks-icon-info-item\">\n    \n<div class=\"wp-block-unilux-blocks-wrapper icon-info\">\n<div class=\"icon--primary icon--secondary-2  wp-block-unilux-blocks-icon-picker\">\n    <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--principal-investigator \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--principal-investigator\"><\/use><\/svg><\/div>\n\n\n<p class=\"has-1-125-rem-font-size\">Principal Investigator(s):<br><strong>Dr. Zhiqiang ZHONG<\/strong><\/p>\n<\/div>\n<\/li>\n    <\/ul>\n<\/div>\n\n\n\n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"about\"\n    >\nAbout<\/h2>\n\n\n\n<p>Zhiqiang Zhong\u2019s YIA project \u201cKDReCell\u201d aims to revolutionize cell reprogramming through foundation Artificial Intelligence models. By combining deep learning with biological knowledge networks, the project seeks to understand and control cell differentiation processes. This interdisciplinary work bridges computer science and cancer biology with direct applications in regenerative medicine, establishing new paradigms for using AI to accelerate biological discovery.<\/p>\n\n\n<div class=\"wp-block-unilux-blocks-spacer is-spacer-size-sm\"><\/div>\n\n\n<p><strong>This project has received funding from the European Union\u2019s Horizon <strong>Europe <\/strong>research and innovation programme under the Marie Sk\u0142odowska-Curie Actions grant agreement 101081455.<\/strong><\/p>\n\n\n<div class=\"wp-block-unilux-blocks-spacer is-spacer-size-sm\"><\/div>\n\n\n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"organisation-and-partners\"\n    >\nOrganisation and partners<\/h2>\n\n\n\n<p><strong>Faculty of Science, Technology and Medicine (FSTM)<\/strong><br><strong>Institute for Advanced Studies (IAS)<\/strong><br><strong>European Commission<\/strong><\/p>\n\n\n<div class=\"py-48 first:pt-0 last:pb-0 wp-block-unilux-blocks-people-list\">\n    \n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"project-team\"\n    >\nProject team<\/h2>\n<ul class=\"flex flex-wrap -mx-16 wp-block-unilux-blocks-people-item-wrapper\">\n    <li class=\"w-full md:w-1\/2 p-16 wp-block-unilux-blocks-people-item-automated\"><div class=\"ulux-card card-people bg-theme\"><div class=\"list-people bg-theme\">\n    <div class=\"list-people__container\">\n        <div class=\"list-people__visual\">\n            <figure class=\"wp-block-dev4-reusable-blocks-image\">\n                <!-- Template Image Component: default -->\n<img decoding=\"async\" class=\"w-full\" width=\"\" height=\"\" rel=\"\" alt=\"Dr. Zhiqiang ZHONG\" src=\"https:\/\/www.uni.lu\/en\/person-image\/NTAwMzEzMDFfX1poaXFpYW5nIFpIT05H\" srcset=\"https:\/\/www.uni.lu\/en\/person-image\/NTAwMzEzMDFfX1poaXFpYW5nIFpIT05H--thumbnail 150w,https:\/\/www.uni.lu\/en\/person-image\/NTAwMzEzMDFfX1poaXFpYW5nIFpIT05H--medium 300w,https:\/\/www.uni.lu\/en\/person-image\/NTAwMzEzMDFfX1poaXFpYW5nIFpIT05H--medium_large 768w,https:\/\/www.uni.lu\/en\/person-image\/NTAwMzEzMDFfX1poaXFpYW5nIFpIT05H--large 1024w,https:\/\/www.uni.lu\/en\/person-image\/NTAwMzEzMDFfX1poaXFpYW5nIFpIT05H--1536x1536 1536w,https:\/\/www.uni.lu\/en\/person-image\/NTAwMzEzMDFfX1poaXFpYW5nIFpIT05H--2048x2048 2048w\" loading=\"lazy\" \/><!-- end Image Component -->\n            <\/figure>\n        <\/div>\n        <div class=\"list-people__body\">\n            <h3 class=\"list-people__title\">Dr. Zhiqiang ZHONG<\/h3>\n            <p class=\"list-people__description\">Postdoctoral researcher<\/p>\n            <div class=\"wp-block-unilux-blocks-simple-cta wp-block-unilux-blocks-people-item-automated\">\n    <a\n        href=\"https:\/\/www.uni.lu\/fstm-en\/people\/zhiqiang-zhong\/\"\n        title=\"Dr. Zhiqiang ZHONG\"\n        class=\"link-text link-text--icon list-people__link link-absolute\"\n        target=\"\"\n    >\n        <span class=\"link-text__body\">\n            <span class=\"link-text__name\">Learn more<\/span>\n        <\/span>\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>    <\/a>\n<\/div>\n        <\/div>\n    <\/div>\n<\/div>\n<\/div><\/li><li class=\"w-full md:w-1\/2 p-16 wp-block-unilux-blocks-people-item-automated\"><div class=\"ulux-card card-people bg-theme\"><div class=\"list-people bg-theme\">\n    <div class=\"list-people__container\">\n        <div class=\"list-people__visual\">\n            <figure class=\"wp-block-dev4-reusable-blocks-image\">\n                <!-- Template Image Component: default -->\n<img decoding=\"async\" class=\"w-full\" width=\"\" height=\"\" rel=\"\" alt=\"Assist. Prof Jun PANG\" src=\"https:\/\/www.uni.lu\/en\/person-image\/NTAwMDI4MDdfX0p1biBQQU5H\" srcset=\"https:\/\/www.uni.lu\/en\/person-image\/NTAwMDI4MDdfX0p1biBQQU5H--thumbnail 150w,https:\/\/www.uni.lu\/en\/person-image\/NTAwMDI4MDdfX0p1biBQQU5H--medium 300w,https:\/\/www.uni.lu\/en\/person-image\/NTAwMDI4MDdfX0p1biBQQU5H--medium_large 768w,https:\/\/www.uni.lu\/en\/person-image\/NTAwMDI4MDdfX0p1biBQQU5H--large 1024w,https:\/\/www.uni.lu\/en\/person-image\/NTAwMDI4MDdfX0p1biBQQU5H--1536x1536 1536w,https:\/\/www.uni.lu\/en\/person-image\/NTAwMDI4MDdfX0p1biBQQU5H--2048x2048 2048w\" loading=\"lazy\" \/><!-- end Image Component -->\n            <\/figure>\n        <\/div>\n        <div class=\"list-people__body\">\n            <h3 class=\"list-people__title\">Assist. Prof Jun PANG<\/h3>\n            <p class=\"list-people__description\">Assistant professor in Computer Science<\/p>\n            <div class=\"wp-block-unilux-blocks-simple-cta wp-block-unilux-blocks-people-item-automated\">\n    <a\n        href=\"https:\/\/www.uni.lu\/fstm-en\/people\/jun-pang\/\"\n        title=\"Assist. Prof Jun PANG\"\n        class=\"link-text link-text--icon list-people__link link-absolute\"\n        target=\"\"\n    >\n        <span class=\"link-text__body\">\n            <span class=\"link-text__name\">Learn more<\/span>\n        <\/span>\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>    <\/a>\n<\/div>\n        <\/div>\n    <\/div>\n<\/div>\n<\/div><\/li><li class=\"w-full md:w-1\/2 p-16 wp-block-unilux-blocks-people-item-automated\"><div class=\"ulux-card card-people bg-theme\"><div class=\"list-people bg-theme\">\n    <div class=\"list-people__container\">\n        <div class=\"list-people__visual\">\n            <figure class=\"wp-block-dev4-reusable-blocks-image\">\n                <!-- Template Image Component: default -->\n<img decoding=\"async\" class=\"w-full\" width=\"\" height=\"\" rel=\"\" alt=\"Prof Daniel ABANKWA\" src=\"https:\/\/www.uni.lu\/en\/person-image\/NTAwMjcwODZfX0RhbmllbCBBQkFOS1dB\" srcset=\"https:\/\/www.uni.lu\/en\/person-image\/NTAwMjcwODZfX0RhbmllbCBBQkFOS1dB--thumbnail 150w,https:\/\/www.uni.lu\/en\/person-image\/NTAwMjcwODZfX0RhbmllbCBBQkFOS1dB--medium 300w,https:\/\/www.uni.lu\/en\/person-image\/NTAwMjcwODZfX0RhbmllbCBBQkFOS1dB--medium_large 768w,https:\/\/www.uni.lu\/en\/person-image\/NTAwMjcwODZfX0RhbmllbCBBQkFOS1dB--large 1024w,https:\/\/www.uni.lu\/en\/person-image\/NTAwMjcwODZfX0RhbmllbCBBQkFOS1dB--1536x1536 1536w,https:\/\/www.uni.lu\/en\/person-image\/NTAwMjcwODZfX0RhbmllbCBBQkFOS1dB--2048x2048 2048w\" loading=\"lazy\" \/><!-- end Image Component -->\n            <\/figure>\n        <\/div>\n        <div class=\"list-people__body\">\n            <h3 class=\"list-people__title\">Prof Daniel ABANKWA<\/h3>\n            <p class=\"list-people__description\">Full professor in Cellular Tumour Biology<\/p>\n            <div class=\"wp-block-unilux-blocks-simple-cta wp-block-unilux-blocks-people-item-automated\">\n    <a\n        href=\"https:\/\/www.uni.lu\/fstm-en\/people\/daniel-abankwa\/\"\n        title=\"Prof Daniel ABANKWA\"\n        class=\"link-text link-text--icon list-people__link link-absolute\"\n        target=\"\"\n    >\n        <span class=\"link-text__body\">\n            <span class=\"link-text__name\">Learn more<\/span>\n        <\/span>\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>    <\/a>\n<\/div>\n        <\/div>\n    <\/div>\n<\/div>\n<\/div><\/li><\/ul>\n\n<\/div>\n\n<\/div><\/section>\n","protected":false},"excerpt":{"rendered":"<p>Zhiqiang Zhong\u2019s YIA project \u201cKDReCell\u201d aims to revolutionize cell reprogramming through foundation Artificial Intelligence models. By combining deep learning with biological knowledge networks, the project seeks to understand and control cell differentiation processes. This interdisciplinary work bridges computer science and cancer biology with direct applications in regenerative medicine, establishing new paradigms for using AI to accelerate biological discovery.<\/p>\n","protected":false},"author":203,"featured_media":12767,"parent":0,"menu_order":0,"template":"","meta":{"featured_image_focal_point":{"x":0.55,"y":0.52},"show_featured_caption":false,"ulux_newsletter_groups":"","uluxPostTitle":"KDReCell","uluxPrePostTitle":"Research project","_trash_the_other_posts":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false,"rpp_rp_identifier":"13104","rpp_taxonomies_in_sync":true},"research-project-status":[],"research-project-type":[],"field-of-interest":[],"organisation":[],"authorship":[203,329],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.3 (Yoast SEO v22.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>KDReCell: Leveraging Knowledge-Enhanced Deep Learning Models for Cell Reprogramming I Uni.lu<\/title>\n<meta name=\"description\" content=\"Zhiqiang Zhong\u2019s YIA project \u201cKDReCell\u201d aims to revolutionize cell reprogramming through foundation Artificial Intelligence models. By combining deep learning with biological knowledge networks, the project seeks to understand and control cell differentiation processes. This interdisciplinary work bridges computer science and cancer biology with direct applications in regenerative medicine, establishing new paradigms for using AI to accelerate biological discovery.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.uni.lu\/research-en\/research-projects\/kdrecell-leveraging-knowledge-enhanced-deep-learning-models-for-cell-reprogramming\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"KDReCell: Leveraging Knowledge-Enhanced Deep Learning Models for Cell Reprogramming\" \/>\n<meta property=\"og:description\" content=\"Zhiqiang Zhong\u2019s YIA project \u201cKDReCell\u201d aims to revolutionize cell reprogramming through foundation Artificial Intelligence models. 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