{"id":14074,"date":"2026-04-29T09:54:59","date_gmt":"2026-04-29T07:54:59","guid":{"rendered":"https:\/\/www.uni.lu\/lcsb-en\/?post_type=events&#038;p=14074"},"modified":"2026-04-29T09:55:01","modified_gmt":"2026-04-29T07:55:01","slug":"artificial-intelligence-for-bioscientific-research-prof-annalisa-barla","status":"publish","type":"events","link":"https:\/\/www.uni.lu\/lcsb-en\/events\/artificial-intelligence-for-bioscientific-research-prof-annalisa-barla\/","title":{"rendered":"Artificial Intelligence for Bioscientific Research &#8211; Prof. Annalisa Barla"},"content":{"rendered":"\n<section class=\"py-0 wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\"><div class=\"wp-block-unilux-blocks-spacer is-spacer-size-md\"><\/div>\n\n\n<p><strong>This is a hybrid event.<\/strong> Join on site or <a href=\"https:\/\/unilu.webex.com\/unilu\/j.php?MTID=macd6636a9192f098e5d407d9eda4b19a\" target=\"_blank\" rel=\"noreferrer noopener\">Tune in via Webex here<\/a>.<\/p>\n\n\n<div class=\"wp-block-unilux-blocks-spacer is-spacer-size-sm\"><\/div>\n\n\n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"navigating-the-complexities-of-machine-learning-in-healthcare-case-studies-insights-and-challenges\"\n    >\n\nNavigating the complexities of machine learning in healthcare: Case studies, insights, and challenges<\/h2>\n\n\n\n<p>Machine learning has emerged as a highly effective approach in healthcare, often outperforming traditional statistical methods. However, to establish machine learning (ML) as a reliable tool in clinical practice, strict adherence to best practices in data handling, experimental design, and model evaluation is required to ensure reproducible and interpretable results. This talk addresses the unique challenges posed by biomedical data, such as high dimensionality, low signal-to-noise ratios, and small sample sizes. Using case studies of neurological disorders we demonstrate how robust variable selection and permutation-based significance assessment can identify reliable biomarkers. The presentation introduces frameworks for addressing methodological complexity and discusses strategies for handling data scarcity through careful cross-validation design. It also highlights critical considerations for translating ML findings into actionable clinical insights while maintaining scientific rigor.<\/p>\n\n\n<div class=\"wp-block-unilux-blocks-spacer is-spacer-size-sm\"><\/div>\n\n\n<div class=\"wp-block-columns is-layout-flex wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<h3 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"about-the-speaker\"\n    >\nAbout the speaker<\/h3>\n\n\n\n<p>Annalisa Barla is an Associate Professor of Computer Science at the University of Genoa and a member of the <a href=\"https:\/\/malga.unige.it\/\" target=\"_blank\" rel=\"noreferrer noopener\">Machine Learning Genoa Center (MaLGa)<\/a>. Her research focuses on machine learning methods for the analysis of complex, high-dimensional data, with particular attention to biomedical applications, robust model selection, interpretability, and reproducibility. She has contributed extensively to the use of machine learning in neurology and life sciences, including studies on multiple sclerosis, epilepsy, and Alzheimer\u2019s disease. More recently, her work has expanded toward the use of machine learning, data visualization, and complex systems approaches to support the understanding of scientific, biomedical, and socio-technical phenomena. This includes the development of methods and tools for making patterns, relationships, and hidden structures in complex data more interpretable and actionable for researchers and domain experts.<\/p>\n\n\n<div class=\"wp-block-unilux-blocks-spacer is-spacer-size-sm\"><\/div>\n\n\n<ul class=\"wp-block-unilux-blocks-quick-link-underline\">\n    \n<li class=\"wp-block-unilux-blocks-quick-link-underline-item\">\n    <a\n            href=\"https:\/\/www.uni.lu\/lcsb-en\/biomedical-data-series\/\"\n            class=\"wp-block-unilux-blocks-anchor\"        target=\"\"\n>\n    \n<span class=\"hero__title__subject wp-block-unilux-blocks-plain-text\">This lecture is part of the Causal Analysis of Biomedical Data Lecture Series<\/span><svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg><\/a>\n<\/li>\n<\/ul><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\"><figure class=\"wp-block-dev4-reusable-blocks-image  object-fit--cover\">\n    \n<img decoding=\"async\" class=\"wp-block-image unilux-custom-image-block\"\n                alt=\"\"\n            src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2026\/04\/29095406\/Screenshot-2026-04-29-at-09.53.35.png\"\n                srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2026\/04\/29095406\/Screenshot-2026-04-29-at-09.53.35-265x300.png 265w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2026\/04\/29095406\/Screenshot-2026-04-29-at-09.53.35-903x1024.png 903w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2026\/04\/29095406\/Screenshot-2026-04-29-at-09.53.35-768x871.png 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2026\/04\/29095406\/Screenshot-2026-04-29-at-09.53.35.png 1226w\"\n                style=\"object-position: 40.00% 49.00%; font-family: &quot;object-fit: cover; object-position: 40.00% 49.00%;&quot;; aspect-ratio: 3\/4; object-fit: cover; width: 100%;\"\n        loading=\"lazy\"\n\/>    <\/figure><\/div>\n<\/div>\n\n\n<div class=\"wp-block-unilux-blocks-spacer is-spacer-size-sm\"><\/div>\n\n\n<p>The Artificial Intelligence for Bioscientific Research Lecture Series is supported by the <a href=\"https:\/\/www.fnr.lu\">Luxembourg National Research Fund<\/a> (FNR) RESCOM Program.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:25%\"><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\"><figure class=\"wp-block-dev4-reusable-blocks-image  object-fit--contain\">\n    \n<img decoding=\"async\" class=\"wp-block-image unilux-custom-image-block\"\n                alt=\"FNR logo\"\n            src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/FNR_LOGO.png\"\n                srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/FNR_LOGO-300x50.png 300w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/FNR_LOGO-1024x172.png 1024w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/FNR_LOGO-768x129.png 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/FNR_LOGO-1536x258.png 1536w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/FNR_LOGO-2048x344.png 2048w\"\n                style=\"object-position: 60.00% 21.00%; font-family: &quot;object-fit: contain; object-position: 60.00% 21.00%;&quot;; aspect-ratio: 32\/9; object-fit: contain; width: 100%;\"\n        loading=\"lazy\"\n\/>    <\/figure><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:25%\"><\/div>\n<\/div>\n<\/div><\/section>\n","protected":false},"excerpt":{"rendered":"<p>This series brings together global experts in causal inference, computational biology and statistics to discuss integrative omics analysis, personalised medicine and public health applications.<\/p>\n","protected":false},"author":351,"featured_media":4839,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"featured_image_focal_point":[],"show_featured_caption":false,"ulux_newsletter_groups":"","uluxPostTitle":"","uluxPrePostTitle":"","_trash_the_other_posts":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false,"event_start_date":"2026-05-04 16:00:00","event_end_date":"2026-05-04 17:00:00","event_speaker_name":"Prof. Annalisa Barla","event_speaker_link":"https:\/\/personal.annalisabarla.it\/","event_is_online":false,"event_location":"Biotech II (BT2)","event_street":"6 Av. du Swing","event_location_link":"https:\/\/unilu.webex.com\/unilu\/j.php?MTID=macd6636a9192f098e5d407d9eda4b19a","event_zip_code":"4367","event_city":"Belvaux","event_country":"Luxembourg"},"events-topic":[306],"events-type":[315,348],"organisation":[204,202],"authorship":[351],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.3 (Yoast SEO v22.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Artificial Intelligence for Bioscientific Research - Prof. Annalisa Barla - LCSB I Uni.lu<\/title>\n<meta name=\"description\" content=\"This series brings together global experts in causal inference, computational biology and statistics to discuss integrative omics analysis, personalised medicine and public health applications.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, 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