{"id":10459,"date":"2025-01-27T14:29:49","date_gmt":"2025-01-27T13:29:49","guid":{"rendered":"https:\/\/www.uni.lu\/lcsb-en\/?post_type=events&#038;p=10459"},"modified":"2025-01-28T12:09:50","modified_gmt":"2025-01-28T11:09:50","slug":"neuroscience-series-gconstantin","status":"publish","type":"events","link":"https:\/\/www.uni.lu\/lcsb-en\/events\/neuroscience-series-gconstantin\/","title":{"rendered":"Neuroscience Lecture Series &#8211; Prof. Gabriela Constantin"},"content":{"rendered":"\n<section class=\"py-0 wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\"><div class=\"wp-block-unilux-blocks-spacer is-spacer-size-md\"><\/div>\n\n\n<p>Explore the forefront of neuroscience with the LCSB Neuroscience Lecture Series, featuring scientific presentations from internationally renowned experts in various disciplines of neuroscience.<\/p>\n\n\n\n<p><strong>Meet the speaker! <\/strong>A networking aperitif with light snacks and refreshments will follow the presentation. Further one-on-one meeting opportunities with the speaker can be arranged by emailing <a href=\"mailto:caroline.belot@uni.lu\">Caroline Belot<\/a>.<\/p>\n\n\n\n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"alterations-of-the-neuro-immune-communication-in-the-development-of-neurodegenerative-diseases\"\n    >\n<strong>Alterations of the neuro-immune communication in the development of neurodegenerative diseases<\/strong><\/h2>\n\n\n\n<p>Inflammation is a pathological hallmark of neurodegenerative diseases, including Alzheimer\u2019s disease (AD), and understanding the underlying mechanisms may facilitate the development of new treatments. It is now clear that dysregulation of peripheral innate and adaptive immune cells may play a key role in the development of neurodegeneration. Particularly, neutrophils have been shown to migrate from the blood into the brain and promote the development of cognitive impairment and neuropathological features in animal models of AD. T cells can also accumulate in the AD brain and contribute to disease development. This presentation will discuss key alterations of the neuro-immune communication in AD, focusing on the dysfunctions of neutrophil and T cell compartments promoting neurotoxic inflammation in AD.<\/p>\n\n\n<div class=\"wp-block-unilux-blocks-spacer is-spacer-size-sm\"><\/div>\n\n\n<div class=\"wp-block-columns is-layout-flex wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<h3 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"about-the-speaker\"\n    >\nAbout the speaker<\/h3>\n\n\n\n<p>Gabriela Constantin is a Professor of Pathology and Immunology at the <a href=\"https:\/\/www.univr.it\/home\" target=\"_blank\" rel=\"noreferrer noopener\">University of Verona<\/a>, Italy. She completed her medical degree and residency in neurology at the <a href=\"https:\/\/www.unimi.it\/en\" target=\"_blank\" rel=\"noreferrer noopener\">University of Milan<\/a> and obtained a PhD at the University of Verona. <a href=\"http:\/\/dp.univr.it\/~constantin\/LONI\/index.html\" target=\"_blank\" rel=\"noreferrer noopener\">Her group<\/a>&#8216;s work centres around the immune and inflammatory mechanisms promoting the development of brain diseases. <\/p>\n\n\n<div class=\"wp-block-unilux-blocks-spacer is-spacer-size-sm\"><\/div>\n\n\n<ul class=\"wp-block-unilux-blocks-quick-link-underline\">\n    \n<li class=\"wp-block-unilux-blocks-quick-link-underline-item\">\n    <a\n            href=\"https:\/\/www.uni.lu\/lcsb-en\/research\/neuroscience-series\/\"\n            class=\"wp-block-unilux-blocks-anchor\"        target=\"\"\n>\n    \n<span class=\"hero__title__subject wp-block-unilux-blocks-plain-text\">This lecture is part of the LCSB Neuroscience Lecture Series<\/span><svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg><\/a>\n<\/li>\n<\/ul><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\"><figure class=\"wp-block-dev4-reusable-blocks-image  object-fit--cover\">\n    \n<img decoding=\"async\" class=\"wp-block-image unilux-custom-image-block\"\n                alt=\"\"\n            src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2025\/01\/Foto-Gabriela-Constantin-.jpg\"\n                srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2025\/01\/Foto-Gabriela-Constantin--300x282.jpg 300w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2025\/01\/Foto-Gabriela-Constantin--1024x963.jpg 1024w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2025\/01\/Foto-Gabriela-Constantin--768x722.jpg 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2025\/01\/Foto-Gabriela-Constantin--1536x1444.jpg 1536w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2025\/01\/Foto-Gabriela-Constantin--2048x1926.jpg 2048w\"\n                style=\"object-position: 48.00% 47.00%; font-family: &quot;object-fit: cover; object-position: 48.00% 47.00%;&quot;; aspect-ratio: 3\/4; object-fit: cover; width: 100%;\"\n        loading=\"lazy\"\n\/>    <\/figure><\/div>\n<\/div>\n\n\n<div class=\"wp-block-unilux-blocks-spacer is-spacer-size-sm\"><\/div>\n\n\n<p>The Neuroscience Lecture Series is supported by the <a href=\"https:\/\/www.fnr.lu\">Luxembourg National Research Fund<\/a> (FNR) RESCOM Program (RESCOM24\/18810230\/Neurosciences_LS).<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:25%\"><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\"><figure class=\"wp-block-dev4-reusable-blocks-image  object-fit--contain\">\n    \n<img decoding=\"async\" class=\"wp-block-image unilux-custom-image-block\"\n                alt=\"FNR logo\"\n            src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/FNR_LOGO.png\"\n                srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/FNR_LOGO-300x50.png 300w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/FNR_LOGO-1024x172.png 1024w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/FNR_LOGO-768x129.png 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/FNR_LOGO-1536x258.png 1536w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/6\/2023\/06\/FNR_LOGO-2048x344.png 2048w\"\n                style=\"object-position: 47.00% 5.00%; font-family: &quot;object-fit: contain; object-position: 47.00% 5.00%;&quot;; aspect-ratio: 16\/9; object-fit: contain; width: 100%;\"\n        loading=\"lazy\"\n\/>    <\/figure><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:25%\"><\/div>\n<\/div>\n<\/div><\/section>\n","protected":false},"excerpt":{"rendered":"<p>Explore the forefront of neuroscience with the LCSB Neuroscience Lecture Series, featuring scientific presentations from internationally renowned experts in various disciplines of neuroscience.<\/p>\n","protected":false},"author":63,"featured_media":2751,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"featured_image_focal_point":[],"show_featured_caption":false,"ulux_newsletter_groups":"","uluxPostTitle":"","uluxPrePostTitle":"","_trash_the_other_posts":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false,"event_start_date":"2025-02-05 11:00:00","event_end_date":"2025-02-05 13:00:00","event_speaker_name":"Prof. Gabriela Gonstantin","event_speaker_link":"https:\/\/www.researchgate.net\/profile\/Gabriela-Constantin-2","event_is_online":false,"event_location":"RIKEN room - Biotech II (BT2)","event_street":"6, avenue du Swing","event_location_link":"https:\/\/maps.app.goo.gl\/Vu3C7cZMFqbd9YCp9","event_zip_code":"4367","event_city":"Belvaux","event_country":"Luxembourg"},"events-topic":[306],"events-type":[315,348],"organisation":[202,216],"authorship":[63],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.3 (Yoast SEO v22.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Neuroscience Lecture: Prof. Dorothee Dormann - LCSB I Uni.lu<\/title>\n<meta name=\"description\" content=\"Explore the forefront of neuroscience with the LCSB Neuroscience Lecture Series, featuring scientific presentations from internationally renowned experts in various disciplines of neuroscience.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, 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