1.0LCSB ENhttps://www.uni.lu/lcsb-enRuxandra Soarehttps://www.uni.lu/lcsb-en/author/chromium/Researchrich600338<blockquote class="wp-embedded-content" data-secret="rCZC8WvR4b"><a href="https://www.uni.lu/lcsb-en/research-groups/gene-expression-dynamics/research/">Research</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://www.uni.lu/lcsb-en/research-groups/gene-expression-dynamics/research/embed/#?secret=rCZC8WvR4b" width="600" height="338" title="“Research” — LCSB EN" data-secret="rCZC8WvR4b" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script>
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The biology of disease is centred on the loss or gain of protein function caused by mutations that alter the protein sequence. Although these mutations undoubtedly contribute to the pathology of disorders, a unifying model of the underlying molecular mechanisms of these diseases is largely lacking. This suggests that important effects of these mutations on protein function have been overlooked.https://www.uni.lu/wp-content/uploads/sites/6/2026/03/03113133/LCSB_SM-Profile_1600x1600px-scaled.jpg25602560