Faculty of Science, Technology and Medicine
Faculty of Law, Economics and Finance
Faculty of Humanities, Education and Social Sciences
Interdisciplinary Centre for Security, Reliability and Trust
Luxembourg Centre for Systems Biomedicine
Luxembourg Centre for Contemporary and Digital History
Luxembourg Centre for European Law
Luxembourg Centre for Socio-Environmental SystemsOur research
Below we summarise research activities in the Bioinformatics Core, focusing on projects in the areas of genome analysis, translational medicine, and visual analytics.
Genome analysis
The Genome Analysis team performs large-scale genomic and genetic analyses in the fields of complex and rare human diseases, in particular Parkinson’s disease (PD) and genetic epilepsies. It is involved in systems genetics projects in humans and other model organisms, works on computational methods to understand the host-microbe interactions, and has developed reproducible workflows for large-scale microbiome multi-omics studies (in close collaboration with the Systems Ecology group of Prof. Paul Wilmes).
| Project | Topic | Contact |
|---|---|---|
| Epi25, For 2715, ILAE Genomics | Epilepsy genomics | Patrick May Roland Krause |
| Treat-ION | Epilepsy genomics | Patrick May |
| LRRK2 family genomics | PD genomics | Patrick May |
| FOR 2488, NCER-PD, JPND Courage PD, GP2, FunMito | PD genetics | Patrick May |
| MICROH DTU, metaPUF, IMP, Binny | Microbiome bioinformatics | Patrick May |
| CLIMAFA | Fanconi anemia genetics | Patrick May |
| PRECIDEM | Dementia genetics | Patrick May |
| Improving the performance of polygenic scores in diverse populations | Genetics | Patrick May |
Contact
Visual analytics
We offer expertise and tools for visualisation, visual exploration, and analytics of complex biological mechanisms. We construct diagrams of molecular mechanisms affected by pathology of different diseases (disease maps), focusing on neurodegeneration and immune pathways.
| Project | Topic | Contact |
|---|---|---|
| Parkinson’s disease map | Parkinson’s disease Application of a disease map | Marek Ostaszewski |
| BY-COVID | COVID-19 Application of a disease map | Marek Ostaszewski |
| MIRIADE | Dementia Data integration, disease maps | Marek Ostaszewski |