{"id":141,"date":"2019-01-03T10:30:27","date_gmt":"2019-01-03T10:30:27","guid":{"rendered":"https:\/\/website.prod.unilu.spikeseed.cloud\/fstm-fr\/news\/ultracentrifuge-and-nanosight-discover-our-new-acquisitions\/"},"modified":"2019-01-03T10:30:27","modified_gmt":"2019-01-03T10:30:27","slug":"ultracentrifuge-and-nanosight-discover-our-new-acquisitions","status":"publish","type":"news","link":"https:\/\/www.uni.lu\/fstm-fr\/news\/ultracentrifuge-and-nanosight-discover-our-new-acquisitions\/","title":{"rendered":"Ultracentrifuge and nanosight: discover our new acquisitions"},"content":{"rendered":"<section class=\"wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\"><p>Thanks to the \u201cFondation Cancer\u201d support, the Life Sciences Research Unit (LSRU) has just acquired two brand new equipment: one ultracentrifuge and one nanosight. These acquisitions will definitely play an important role in the current and future research activities of the Research Unit. But what exactly is an ultracentrifuge and a nanosight? What can they do?<\/p><p>The <strong>ultracentrifuge<\/strong> aims to isolate extracellular vesicles, which are small vesicles (30-180 nm), transferring biomolecules such as proteins, mRNAs, non-coding RNAs and metabolites. This can reach high speed, until 50.000 round per minute, to isolate tiny particles (or viruses), which have very low densities. On the other side, the <strong>nanosight<\/strong> measures the size of very small particles between 10\/40 to 1000\/2000 nm and the concentration of particles from 10<sup>6<\/sup> to 10<sup>9<\/sup>\u00a0particles \/ mL, such as extracellular vesicles.<\/p><p>\u201cThe ultracentrifuge and nanosight have been particularly used for our current project called SecMelPro\u201d, explains <a href=\"https:\/\/wwwen.uni.lu\/research\/fstc\/life_sciences_research_unit\/research_areas\/signal_transduction\/people\/geoffroy_walbrecq\" target=\"_blank\" title=\"\" rel=\"noopener\">Geoffroy Walbrecq<\/a>, Postdoctoral researcher at the <a href=\"https:\/\/wwwen.uni.lu\/research\/fstc\/life_sciences_research_unit\" target=\"_blank\" title=\"\" rel=\"noopener\">Life Sciences Research Unit (LSRU)<\/a>. This project actually aims to investigate <strong>the role of the secretome<\/strong>, which is the macromolecules released by the cells (including cytokines and extracellular vesicles) on the melanoma tumor microenvironment as well as <strong>the influence of hypoxia<\/strong> (lack of oxygen) on this crosstalk.<\/p><figure class=\"wp-block-dev4-reusable-blocks-image  object-fit--contain\">\n    \n<img decoding=\"async\" class=\"wp-block-image unilux-custom-image-block\"\n                alt=\"\"\n            src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/20\/2023\/07\/odile_lecha_and_geoffroy_walbrecq.jpg\"\n                srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/20\/2023\/07\/odile_lecha_and_geoffroy_walbrecq-300x225.jpg 300w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/20\/2023\/07\/odile_lecha_and_geoffroy_walbrecq-1024x768.jpg 1024w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/20\/2023\/07\/odile_lecha_and_geoffroy_walbrecq-768x576.jpg 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/20\/2023\/07\/odile_lecha_and_geoffroy_walbrecq-1536x1152.jpg 1536w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/20\/2023\/07\/odile_lecha_and_geoffroy_walbrecq.jpg 2016w\"\n                style=\"object-position: 50.00% 50.00%; font-family: &quot;object-fit: contain; object-position: 50.00% 50.00%;&quot;; aspect-ratio: 4\/3; object-fit: contain; width: 100%;\"\n        loading=\"lazy\"\n\/>    <\/figure><p><strong><i>Geoffroy Walbrecq and\u00a0Odile Lecha with the nanosight<\/i><\/strong><\/p><p>As more and more research teams also investigate the content and the role of extracellular vesicles, both equipment are very useful to the entire Life Sciences Research Unit (LSRU) as well as to other research teams in the country, <strong>within and outside the University of Luxembourg<\/strong>: the <a href=\"https:\/\/lns.lu\/\" target=\"_blank\" title=\"\" rel=\"noopener\">Laboratoire National de Sant\u00e9<\/a> (LNS), the <a href=\"https:\/\/wwwen.uni.lu\/lcsb\" target=\"_blank\" title=\"\" rel=\"noopener\">Luxembourg Centre for Systems Biomedicine<\/a> (LCSB), <a href=\"https:\/\/www.lih.lu\/\" target=\"_blank\" title=\"\" rel=\"noopener\">Luxembourg Institute of Health<\/a> (LIH), etc.<\/p><p><\/p><p>Since its creation in 1994, the\u00a0<a href=\"http:\/\/www.cancer.lu\/\" target=\"_blank\" title=\"\" rel=\"noopener\">Fondation Cancer<\/a>\u00a0is involved in cancer prevention, in cancer patient support and in funding cancer research.\u00a0<\/p><\/div><\/section>","protected":false},"excerpt":{"rendered":"<p>Thanks to the \u201cFondation Cancer\u201d support, the Life Sciences Research Unit (LSRU) has just acquired two brand new equipment: one ultracentrifuge and one nanosight. These acquisitions will definitely play an important role in the current and future research activities of the Research Unit. But what exactly is an ultracentrifuge and a nanosight? What can they do?<\/p>\n","protected":false},"author":0,"featured_media":142,"template":"","format":"standard","meta":{"featured_image_focal_point":[],"show_featured_caption":false,"ulux_newsletter_groups":"","uluxPostTitle":"","uluxPrePostTitle":"","_trash_the_other_posts":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false},"news-category":[],"news-topic":[],"organisation":[24],"authorship":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.3 (Yoast SEO v22.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Ultracentrifuge and nanosight: discover our new acquisitions - FSTM actualit\u00e9s I Universit\u00e9 du Luxembourg<\/title>\n<meta name=\"description\" content=\"Thanks to the \u201cFondation Cancer\u201d support, the Life Sciences Research Unit (LSRU) has just acquired two brand new equipment: one ultracentrifuge and one nanosight. 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