{"id":7344,"date":"2021-11-04T14:02:08","date_gmt":"2021-11-04T13:02:08","guid":{"rendered":"https:\/\/www.uni.lu\/fstm-en\/events\/phd-thesis-defense-emanuele-penocchio\/"},"modified":"2024-06-20T11:36:58","modified_gmt":"2024-06-20T09:36:58","slug":"doctoral-thesis-defence-emanuele-penocchio","status":"publish","type":"events","link":"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/","title":{"rendered":"Doctoral Thesis Defence: Emanuele Penocchio"},"content":{"rendered":"\n
\n

Thermodynamics of Chemical Engines: A Chemical Reaction Network Approach<\/strong><\/p>\n\n\n\n

Chemical processes in closed systems inevitably relax to equilibrium. Energy can be employed to counteract such tendency and drive reactions against their spontaneous direction. This nonequilibrium driving is implemented in open systems, which living organisms provide the most spectacular examples of. In recent years, experiments in supramolecular chemistry, photochemistry and electrochemistry demonstrated that, by opening synthetic systems to matter and\/or energy exchanges with the environment, artificial systems with life-like behaviours can be realized and used to convert energy inputs of different nature into work at both the nanoscopic and the macroscopic level. However, one tool that is still lacking is a firm grasp of the thermodynamics of these chemical engines<\/i>. In this thesis, we provide it by leveraging the most recent developments of the thermodynamic description of deterministic chemical reaction networks. As main theoretical results, we extend the current theory to encompass nonideal and light-driven systems, thus providing the fundamental tools to treat electrochemical and photochemical systems in addition to the chemically driven ones. We also expand the scope of information thermodynamics to bipartite chemical reaction networks characterized by macroscopic non-normalized concentration distributions evolving in time with nonlinear dynamics. This framework potentially applies to almost every synthetic chemical engine realized until now, and to many models of biological systems too. Here, we undertake the thermodynamic analysis of some of the epitomes in the field of artificial chemical engines: a model of chemically driven self-assembly, an experimental chemically driven molecular motor, and an experimental photochemical bimolecular pump. The thesis provides a thermodynamic level of understanding of chemical engines that is general, complements previous analyses based on kinetics and stochastic thermodynamics, and has practical implications for designing and improving synthetic systems, regardless of the particular type of powering or chemical structure.<\/p>\n\n\n\n

Dissertation defence jury<\/strong><\/p>\n\n\n\n

Chair: Professor Alexander Skupin, Universit\u00e9 du Luxembourg, Luxembourg Centre for Systems Biomedicine (LCSB)<\/i><\/p>\n\n\n\n

Vice-Chair: Professor Etienne Fodor, Universit\u00e9 du Luxembourg<\/i><\/p>\n\n\n\n

Supervisor (Member): Professor Massimiliano Esposito, Universit\u00e9 du Luxembourg<\/i><\/p>\n\n\n\n

Member: Professor Thomas Hermans, Universit\u00e9 de Strasbourg, Institut de Science et d\u2019Ing\u00e9nierie Supramol\u00e9culaires (ISIS)<\/i><\/p>\n\n\n\n

Member: Professor David Sivak, Simon Fraser University<\/i><\/p>\n<\/div><\/section>\n","protected":false},"excerpt":{"rendered":"

Thermodynamics of Chemical Engines: A Chemical Reaction Network Approach<\/p>\n","protected":false},"author":33,"featured_media":7345,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"featured_image_focal_point":[],"show_featured_caption":false,"ulux_newsletter_groups":"","uluxPostTitle":"","uluxPrePostTitle":"","_trash_the_other_posts":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false,"event_start_date":"2022-03-30 16:00:00","event_end_date":"2022-03-30 18:00:00","event_speaker_name":"Emanuele Penocchio, under the supervision of Prof. Dr. Massimiliano Esposito","event_speaker_link":"","event_is_online":false,"event_location":"Campus Limpertsberg, B\u00e2timent des Sciences, BS 0.03 ","event_street":"","event_location_link":"","event_zip_code":"1511","event_city":"Luxembourg","event_country":"LU"},"events-topic":[315],"events-type":[327],"organisation":[80,30,29],"authorship":[33],"acf":[],"yoast_head":"\nDoctoral Thesis Defence: Emanuele Penocchio - FSTM events I Uni.lu<\/title>\n<meta name=\"description\" content=\"Thermodynamics of Chemical Engines: A Chemical Reaction Network Approach\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Doctoral Thesis Defence: Emanuele Penocchio\" \/>\n<meta property=\"og:description\" content=\"Thermodynamics of Chemical Engines: A Chemical Reaction Network Approach\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/\" \/>\n<meta property=\"og:site_name\" content=\"FSTM EN\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/fstm.uni.lu\/\" \/>\n<meta property=\"article:modified_time\" content=\"2024-06-20T09:36:58+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/4\/2021\/11\/default.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1500\" \/>\n\t<meta property=\"og:image:height\" content=\"1125\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/\",\"url\":\"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/\",\"name\":\"Doctoral Thesis Defence: Emanuele Penocchio - FSTM events I Uni.lu\",\"isPartOf\":{\"@id\":\"https:\/\/www.uni.lu\/fstm-en\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/4\/2021\/11\/default.jpg\",\"datePublished\":\"2021-11-04T13:02:08+00:00\",\"dateModified\":\"2024-06-20T09:36:58+00:00\",\"description\":\"Thermodynamics of Chemical Engines: A Chemical Reaction Network Approach\",\"breadcrumb\":{\"@id\":\"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/#breadcrumb\"},\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/#primaryimage\",\"url\":\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/4\/2021\/11\/default.jpg\",\"contentUrl\":\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/4\/2021\/11\/default.jpg\",\"width\":1500,\"height\":1125},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.uni.lu\/en\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Faculty of Science, Technology and Medicine\",\"item\":\"https:\/\/www.uni.lu\/fstm-en\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Events\",\"item\":\"https:\/\/www.uni.lu\/fstm-en\/events\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Doctoral Thesis Defence: Emanuele Penocchio\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.uni.lu\/fstm-en\/#website\",\"url\":\"https:\/\/www.uni.lu\/fstm-en\/\",\"name\":\"FSTM\",\"description\":\"Faculty of Science, Technology and Medicine I Uni.lu\",\"publisher\":{\"@id\":\"https:\/\/www.uni.lu\/fstm-en\/#organization\"},\"alternateName\":\"Faculty of Science, Technology and Medicine I University of Luxembourg\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.uni.lu\/fstm-en\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-GB\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.uni.lu\/fstm-en\/#organization\",\"name\":\"FSTM - University of Luxembourg I Uni.lu\",\"alternateName\":\"Faculty of Science, Technology and Medicine\",\"url\":\"https:\/\/www.uni.lu\/fstm-en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/www.uni.lu\/fstm-en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/4\/2026\/03\/03111650\/FSTM_SM-Profile_1600x1600px-scaled.jpg\",\"contentUrl\":\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/4\/2026\/03\/03111650\/FSTM_SM-Profile_1600x1600px-scaled.jpg\",\"width\":2560,\"height\":2560,\"caption\":\"FSTM - University of Luxembourg I Uni.lu\"},\"image\":{\"@id\":\"https:\/\/www.uni.lu\/fstm-en\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/fstm.uni.lu\/\",\"https:\/\/www.linkedin.com\/showcase\/fstm-uni-lu\"]}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Doctoral Thesis Defence: Emanuele Penocchio - FSTM events I Uni.lu","description":"Thermodynamics of Chemical Engines: A Chemical Reaction Network Approach","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/","og_locale":"en_GB","og_type":"article","og_title":"Doctoral Thesis Defence: Emanuele Penocchio","og_description":"Thermodynamics of Chemical Engines: A Chemical Reaction Network Approach","og_url":"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/","og_site_name":"FSTM EN","article_publisher":"https:\/\/www.facebook.com\/fstm.uni.lu\/","article_modified_time":"2024-06-20T09:36:58+00:00","og_image":[{"width":1500,"height":1125,"url":"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/4\/2021\/11\/default.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Estimated reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/","url":"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/","name":"Doctoral Thesis Defence: Emanuele Penocchio - FSTM events I Uni.lu","isPartOf":{"@id":"https:\/\/www.uni.lu\/fstm-en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/#primaryimage"},"image":{"@id":"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/#primaryimage"},"thumbnailUrl":"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/4\/2021\/11\/default.jpg","datePublished":"2021-11-04T13:02:08+00:00","dateModified":"2024-06-20T09:36:58+00:00","description":"Thermodynamics of Chemical Engines: A Chemical Reaction Network Approach","breadcrumb":{"@id":"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/#breadcrumb"},"inLanguage":"en-GB","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/"]}]},{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/#primaryimage","url":"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/4\/2021\/11\/default.jpg","contentUrl":"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/4\/2021\/11\/default.jpg","width":1500,"height":1125},{"@type":"BreadcrumbList","@id":"https:\/\/www.uni.lu\/fstm-en\/events\/doctoral-thesis-defence-emanuele-penocchio\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.uni.lu\/en"},{"@type":"ListItem","position":2,"name":"Faculty of Science, Technology and Medicine","item":"https:\/\/www.uni.lu\/fstm-en\/"},{"@type":"ListItem","position":3,"name":"Events","item":"https:\/\/www.uni.lu\/fstm-en\/events\/"},{"@type":"ListItem","position":4,"name":"Doctoral Thesis Defence: Emanuele Penocchio"}]},{"@type":"WebSite","@id":"https:\/\/www.uni.lu\/fstm-en\/#website","url":"https:\/\/www.uni.lu\/fstm-en\/","name":"FSTM","description":"Faculty of Science, Technology and Medicine I Uni.lu","publisher":{"@id":"https:\/\/www.uni.lu\/fstm-en\/#organization"},"alternateName":"Faculty of Science, Technology and Medicine I University of Luxembourg","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.uni.lu\/fstm-en\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-GB"},{"@type":"Organization","@id":"https:\/\/www.uni.lu\/fstm-en\/#organization","name":"FSTM - University of Luxembourg I Uni.lu","alternateName":"Faculty of Science, Technology and Medicine","url":"https:\/\/www.uni.lu\/fstm-en\/","logo":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/www.uni.lu\/fstm-en\/#\/schema\/logo\/image\/","url":"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/4\/2026\/03\/03111650\/FSTM_SM-Profile_1600x1600px-scaled.jpg","contentUrl":"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/4\/2026\/03\/03111650\/FSTM_SM-Profile_1600x1600px-scaled.jpg","width":2560,"height":2560,"caption":"FSTM - University of Luxembourg I Uni.lu"},"image":{"@id":"https:\/\/www.uni.lu\/fstm-en\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/fstm.uni.lu\/","https:\/\/www.linkedin.com\/showcase\/fstm-uni-lu"]}]}},"_links":{"self":[{"href":"https:\/\/www.uni.lu\/fstm-en\/wp-json\/wp\/v2\/events\/7344"}],"collection":[{"href":"https:\/\/www.uni.lu\/fstm-en\/wp-json\/wp\/v2\/events"}],"about":[{"href":"https:\/\/www.uni.lu\/fstm-en\/wp-json\/wp\/v2\/types\/events"}],"author":[{"embeddable":true,"href":"https:\/\/www.uni.lu\/fstm-en\/wp-json\/wp\/v2\/users\/33"}],"replies":[{"embeddable":true,"href":"https:\/\/www.uni.lu\/fstm-en\/wp-json\/wp\/v2\/comments?post=7344"}],"version-history":[{"count":3,"href":"https:\/\/www.uni.lu\/fstm-en\/wp-json\/wp\/v2\/events\/7344\/revisions"}],"predecessor-version":[{"id":19147,"href":"https:\/\/www.uni.lu\/fstm-en\/wp-json\/wp\/v2\/events\/7344\/revisions\/19147"}],"wp:authorship":[{"embeddable":true,"href":"https:\/\/www.uni.lu\/fstm-en\/wp-json\/wp\/v2\/users\/33"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.uni.lu\/fstm-en\/wp-json\/wp\/v2\/media\/7345"}],"wp:attachment":[{"href":"https:\/\/www.uni.lu\/fstm-en\/wp-json\/wp\/v2\/media?parent=7344"}],"wp:term":[{"taxonomy":"events-topic","embeddable":true,"href":"https:\/\/www.uni.lu\/fstm-en\/wp-json\/wp\/v2\/events-topic?post=7344"},{"taxonomy":"events-type","embeddable":true,"href":"https:\/\/www.uni.lu\/fstm-en\/wp-json\/wp\/v2\/events-type?post=7344"},{"taxonomy":"organisation","embeddable":true,"href":"https:\/\/www.uni.lu\/fstm-en\/wp-json\/wp\/v2\/organisation?post=7344"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}