{"id":672,"date":"2019-12-17T09:53:50","date_gmt":"2019-12-17T09:53:50","guid":{"rendered":"https:\/\/website.prod.unilu.spikeseed.cloud\/fr\/news\/surfing-on-quantum-waves-protein-folding-revisited\/"},"modified":"2019-12-17T09:53:50","modified_gmt":"2019-12-17T09:53:50","slug":"surfing-on-quantum-waves-protein-folding-revisited","status":"publish","type":"news","link":"https:\/\/www.uni.lu\/fr\/news\/surfing-on-quantum-waves-protein-folding-revisited\/","title":{"rendered":"Surfing on Quantum Waves: protein folding revisited"},"content":{"rendered":"

Two physicists\u00a0from the University of Luxembourg have now unambiguously shown that quantum-mechanical wavelike interactions are indeed crucial even at the scale of natural biological processes.<\/p>

Quantum wavelike behaviour plays a key role in modern science and technology, with applications of quantum mechanics ranging from lasers, high-speed fiber communications, to quantum computers and photosynthesis in plants. A natural question is whether quantum wave phenomena<\/strong> could also be relevant for structure formation and dynamical processes in biological systems in living cells<\/strong>. This question has not been addressed convincingly up to now due to the lack of efficient quantum methods that are applicable to systems as large as whole proteins under physiological conditions (i.e. solvated in water and at room temperature).\u00a0<\/p>

\n \n\"\"\n <\/figure>

Now writing in Science Advances<\/strong> – a prestigious multidisciplinary journal published by the American Association for the Advancement of Science (AAAS) – folding process of proteins in water using a fully quantum-mechanical treatment<\/strong> and doctoral researcher\u00a0Prof. Alexandre Tkatchenko<\/a>\u00a0from the Martin St\u00f6hr at the University of Luxembourg have investigated the Department of Physics and Materials Science<\/a> for the first time. Protein folding is the physical process by which a chain of aminoacids acquires its native biologically functional structure due to interactions between aminoacids and the influence of surrounding water. A key novel finding of the present study is that the interaction between the protein and the surrounding water has to be described by quantum-mechanical wavelike behavior, which also turns out to be critical in the dynamics of the protein folding process.\u00a0<\/p>

\u00ab\u00a0The persistence of quantum wavelike behavior in biomolecular systems opens up a new paradigm for explaining some of the fundamental processes in biology\u00a0\u00bb, says Martin St\u00f6hr, the first author of the study. A correct microscopic understanding of biological processes is key to specifically target the function and dysfunction in cells as desired in modern medicine, for instance.\u00a0<\/p>

\u00ab\u00a0Going ahead, we foresee a major role of quantum interactions for the biomolecular machinery ranging from protein assembly to the function of enzymes\u00a0\u00bb, explains Prof.\u00a0Alexandre Tkatchenko, the corresponding author of the study.\u00a0<\/p>

As part of various national and international collaborations, the results of this study have already motivated further comprehensive investigations of how quantum effects can shape a variety of biological phenomena.<\/p>

Publication: \u00ab\u00a0Quantum mechanics of proteins in explicit water: The role of plasmon-like solute-solvent interactions<\/a>\u00ab\u00a0, Science Advances, December 2019<\/p><\/div><\/section>","protected":false},"excerpt":{"rendered":"

Two physicists\u00a0from the University of Luxembourg have now unambiguously shown that quantum-mechanical wavelike interactions are indeed crucial even at the scale of natural biological processes.<\/p>\n","protected":false},"author":0,"featured_media":0,"template":"","format":"standard","meta":{"featured_image_focal_point":[],"show_featured_caption":false,"ulux_newsletter_groups":"","uluxPostTitle":"","uluxPrePostTitle":"","_trash_the_other_posts":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false},"news-category":[4,3],"news-topic":[21],"organisation":[76,25,226],"authorship":[],"acf":[],"yoast_head":"\nSurfing on Quantum Waves: protein folding revisited - 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