{"id":9052,"date":"2022-10-17T11:26:16","date_gmt":"2022-10-17T09:26:16","guid":{"rendered":"https:\/\/www.uni.lu\/fr\/events\/inaugural-lecture-prof-dirk-brenner\/"},"modified":"2022-10-17T11:26:16","modified_gmt":"2022-10-17T09:26:16","slug":"inaugural-lecture-prof-dirk-brenner","status":"publish","type":"events","link":"https:\/\/www.uni.lu\/fr\/events\/inaugural-lecture-prof-dirk-brenner\/","title":{"rendered":"Inaugural Lecture Prof. Dirk Brenner"},"content":{"rendered":"<section class=\"wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\"><p><strong>Mechanisms of acute and chronic inflammation: cROSsing borders between immunology and metabolism<\/strong><\/p><p>The immune system is crucial for a healthy body function and protects us from severe infection. However, diseases driven by a dysregulated immune system are quite diverse in character. Patients with a hyperreactive immune response may develop autoimmunity or chronic inflammation, whereas those with a hyporeactive immune system are immunodeficient and may suffer from infections or tumors. Many immune-mediated diseases do share common inflammatory pathways, and studying these pathways has led to new therapeutics and strategies that have revolutionised treatment. In appropriate metabolic programs in activated immune cells underlie many aberrant immune responses, including disease initiation and progression. Investigating immune cell metabolism with an eye to interfering with detrimental responses is a very promising approach to treating immune-mediated diseases and has the potential to initiate the next wave of innovative immunotherapies.<\/p><p><strong>About the speaker<\/strong><\/p><p>Dirk Brenner joined the Luxembourg Centre for Systems Biomedicine (LCSB) in June 2020 as \u2018Full Professor of Immunology and Genetics\u2019. In 2015, an FNR-ATTRACT Consolidator Fellowship brought him to the Luxembourg Institute of Health (LIH) where he leads the \u2018Experimental &#038; Molecular Immunology\u2019 lab (EMI). He is an immunologist who connects molecular, metabolic principles with the regulation of inflammatory diseases and cancer. Before coming to Luxembourg, he was a postdoctoral fellow at the Ontario Cancer Institute in Toronto, Canada in the laboratory of Prof. Tak W. Mak, where he studied cellular signaling cascades in immune cells. He received his PhD degree at the German Cancer Research Center (DKFZ, Heidelberg, Germany) in the group of Prof. Peter H. Krammer for his work on cell death in the immune system.<\/p><p>His major interests lie in unraveling metabolic and molecular regulatory circuits within the adaptive and the innate immune system. By integrating in vitro with in vivo studies his group aims to gain a comprehensive picture of inflammation and cancer. The group\u2019s vision is to develop new concepts for personalised medicine to mitigate inflammatory diseases through a mechanism-centered approach.<\/p><p><\/p><p><strong>The lecture starts at 17:00 followed by a reception<\/strong><\/p><p><strong>Registration<\/strong><\/p><p>Registration is free but mandatory. Please <a href=\"https:\/\/www.eventbrite.co.uk\/e\/inaugural-lecture-prof-brenner-tickets-403885942727\" target=\"_blank\" title=\"\" rel=\"noopener\">register via Eventbrite<\/a> until 16 November.<\/p><\/div><\/section>","protected":false},"excerpt":{"rendered":"<p>Mechanisms of acute and chronic inflammation: cROSsing borders between immunology and metabolismThe immune system is crucial for a healthy body function and protects us from severe infection. However, diseases driven by a dysregulated immune system are quite diverse in character. Patients with a hyperreactive immune response may develop autoimmunity or chronic inflammation, whereas those with a hyporeactive immune system are immunodeficient and may suffer from infections or tumors. Many immune-mediated diseases do share common inflammatory pathways, and studying these pathways has led to new therapeutics and strategies that have revolutionised treatment. In appropriate metabolic programs in activated immune cells underlie many aberrant immune responses, including disease initiation and progression. Investigating immune cell metabolism with an eye to interfering with detrimental responses is a very promising approach to treating immune-mediated diseases and has the potential to initiate the next wave of innovative immunotherapies.<\/p>\n","protected":false},"author":0,"featured_media":9053,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"closed","template":"","format":"standard","meta":{"featured_image_focal_point":[],"show_featured_caption":false,"ulux_newsletter_groups":"","uluxPostTitle":"","uluxPrePostTitle":"","_trash_the_other_posts":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false,"event_start_date":"2022-11-23 17:00:00","event_end_date":"2022-11-23 18:00:00","event_speaker_name":"Prof. Dirk Brenner","event_speaker_link":"","event_is_online":false,"event_location":"Maison du Savoir (MSA) Auditorium 3.330 (3rd floor)","event_street":"2, avenue de l'Universit\u00e9","event_location_link":"","event_zip_code":"4365","event_city":"Esch-sur-Alzette","event_country":"LU"},"events-topic":[],"events-type":[],"organisation":[202,226],"authorship":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.3 (Yoast SEO v22.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Inaugural Lecture Prof. Dirk Brenner - Universit\u00e9 du Luxembourg<\/title>\n<meta name=\"description\" content=\"Mechanisms of acute and chronic inflammation: cROSsing borders between immunology and metabolismThe immune system is crucial for a healthy body function and protects us from severe infection. However, diseases driven by a dysregulated immune system are quite diverse in character. Patients with a hyperreactive immune response may develop autoimmunity or chronic inflammation, whereas those with a hyporeactive immune system are immunodeficient and may suffer from infections or tumors. Many immune-mediated diseases do share common inflammatory pathways, and studying these pathways has led to new therapeutics and strategies that have revolutionised treatment. In appropriate metabolic programs in activated immune cells underlie many aberrant immune responses, including disease initiation and progression. Investigating immune cell metabolism with an eye to interfering with detrimental responses is a very promising approach to treating immune-mediated diseases and has the potential to initiate the next wave of innovative immunotherapies.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.uni.lu\/fr\/events\/inaugural-lecture-prof-dirk-brenner\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Inaugural Lecture Prof. Dirk Brenner\" \/>\n<meta property=\"og:description\" content=\"Mechanisms of acute and chronic inflammation: cROSsing borders between immunology and metabolismThe immune system is crucial for a healthy body function and protects us from severe infection. However, diseases driven by a dysregulated immune system are quite diverse in character. Patients with a hyperreactive immune response may develop autoimmunity or chronic inflammation, whereas those with a hyporeactive immune system are immunodeficient and may suffer from infections or tumors. Many immune-mediated diseases do share common inflammatory pathways, and studying these pathways has led to new therapeutics and strategies that have revolutionised treatment. In appropriate metabolic programs in activated immune cells underlie many aberrant immune responses, including disease initiation and progression. Investigating immune cell metabolism with an eye to interfering with detrimental responses is a very promising approach to treating immune-mediated diseases and has the potential to initiate the next wave of innovative immunotherapies.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.uni.lu\/fr\/events\/inaugural-lecture-prof-dirk-brenner\/\" \/>\n<meta property=\"og:site_name\" content=\"UNI FR\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/uni.lu\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/11\/2026\/03\/03120045\/UNIV_SM-Profile_1600x1600px-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"2560\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.uni.lu\/fr\/events\/inaugural-lecture-prof-dirk-brenner\/\",\"url\":\"https:\/\/www.uni.lu\/fr\/events\/inaugural-lecture-prof-dirk-brenner\/\",\"name\":\"Inaugural Lecture Prof. Dirk Brenner - Universit\u00e9 du Luxembourg\",\"isPartOf\":{\"@id\":\"https:\/\/www.uni.lu\/fr\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.uni.lu\/fr\/events\/inaugural-lecture-prof-dirk-brenner\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.uni.lu\/fr\/events\/inaugural-lecture-prof-dirk-brenner\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/11\/2022\/10\/inaugural_lecture_prof_dirk_brenner.jpg\",\"datePublished\":\"2022-10-17T09:26:16+00:00\",\"dateModified\":\"2022-10-17T09:26:16+00:00\",\"description\":\"Mechanisms of acute and chronic inflammation: cROSsing borders between immunology and metabolismThe immune system is crucial for a healthy body function and protects us from severe infection. 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