{"id":8015,"date":"2019-10-15T13:20:31","date_gmt":"2019-10-15T11:20:31","guid":{"rendered":"https:\/\/www.uni.lu\/fr\/events\/palaeoproteomic-analysis-for-cultural-heritage-and-molecular-phylogeny-beyond-the-limits-of-ancient-dna\/"},"modified":"2019-10-15T13:20:31","modified_gmt":"2019-10-15T11:20:31","slug":"palaeoproteomic-analysis-for-cultural-heritage-and-molecular-phylogeny-beyond-the-limits-of-ancient-dna","status":"publish","type":"events","link":"https:\/\/www.uni.lu\/fr\/events\/palaeoproteomic-analysis-for-cultural-heritage-and-molecular-phylogeny-beyond-the-limits-of-ancient-dna\/","title":{"rendered":"Palaeoproteomic analysis for cultural heritage and molecular phylogeny beyond the limits of ancient DNA"},"content":{"rendered":"<section class=\"wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\">\n<h3 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"about-the-topic\"\n    >\nAbout the topic\u00a0<\/h3>\n<p>Although the\u00a0first sporadic attempts to detect and sequence ancient protein residues\u00a0did not allow routine and confident sequencing of limited amounts of\u00a0highly degraded protein residues, these limitations were\u00a0eventually\u00a0overcome with the application of the proteomics technology based on\u00a0high-resolution tandem mass spectrometry. It\u00a0is by now consistently demonstrated that\u00a0ancient\u00a0proteins\u00a0represent a more durable source of genetic information, recently\u00a0reported to survive up to\u00a0~1.75 and 3.8 million years (Ma), in dental enamel\u00a0and eggshells respectively. Their sequences can be reliably used to confidently\u00a0reconstruct the\u00a0evolutionary relationships between extant and extinct species. Furthermore, palaeoproteomics demonstrated to be very useful also analyse ancient protein residues\u00a0for biomolecular diagnostics and conservation of\u00a0cultural heritage\u00a0material. Due to their chemical and mechanical properties, proteins have always represented the category of biomolecules most extensively\u00a0exploited by humans to satisfy basic needs, such as nutrition, clothing, sheltering and transportation, as well as artistic expression and abstract thinking.<\/p>\n<h3 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"about-the-speaker\"\n    >\nAbout the speaker<\/h3>\n<p>Initially trained in biochemistry and molecular biology at the University of Turin (Italy), <a href=\"https:\/\/research.ku.dk\/search\/?pure=en%2Fpersons%2Fenrico-cappellini(19d65cd2-a520-485f-a04a-5e993cc7b48a).html\" target=\"_blank\" title=\"\" rel=\"noopener\">Enrico Cappellini<\/a> then expanded his expertise in proteomics and investigation of ancient proteins and DNA. He was trained in analysis of ancient DNA from archaeological human remains (Cappellini et al., Journal of Archaeological Science 2004) and he received his PhD at the University of Florence (Italy) in 2003. During his post-doctoral activity at the University of York (UK) he continued working on ancient DNA and started characterisation of ancient protein residues by amino acid racemisation analysis and MS-based proteomics (Willerslev, Cappellini et al., Science 2007, Cappellini et al., Naturwissenschaften 2010). He moved to the Centre for GeoGenetics, Natural History Museum of Denmark (SNM), University of Copenhagen (DK), in 2009 and he continued applying proteomics techniques to ancient samples in collaboration with colleagues at the Novo Nordisk Foundation center for Protein Research (CPR). With his team, they published the first ancient proteome (Cappellini et al., JPR, 2012) and the first ancient oral metaproteome (Warinner et al., Nature Genetics, 2014). As a demonstration of his prominent role in paleoproteomics investigation he was invited to submit a \u201cPerspective\u201d piece by the multidisciplinary scientific magazine \u201cScience\u201d.\u00a0In October 2016, he was appointed Associate Professor in Paleoproteomics at SNM to start his own research group.<\/p><\/div><\/section>","protected":false},"excerpt":{"rendered":"","protected":false},"author":0,"featured_media":8016,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"closed","template":"","format":"standard","meta":{"featured_image_focal_point":[],"show_featured_caption":false,"ulux_newsletter_groups":"","uluxPostTitle":"","uluxPrePostTitle":"","_trash_the_other_posts":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false,"event_start_date":"2019-11-25 13:00:00","event_end_date":"2019-11-25 16:00:00","event_speaker_name":"Prof. Enrico Cappellini, University of Copenhagen","event_speaker_link":"","event_is_online":false,"event_location":"Universit\u00e9 du Luxembourg, Belval campus, Biotech II","event_street":"","event_location_link":"","event_zip_code":"","event_city":"","event_country":"LU"},"events-topic":[314],"events-type":[],"organisation":[96,25,226],"authorship":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.3 (Yoast SEO v22.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Palaeoproteomic analysis for cultural heritage and molecular phylogeny beyond the limits of ancient DNA - Universit\u00e9 du Luxembourg<\/title>\n<meta name=\"description\" content=\"Although the\u00a0first sporadic attempts to detect and sequence ancient protein residues\u00a0did not allow routine and confident sequencing of limited amounts\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, 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