{"version":"1.0","provider_name":"UNI FR","provider_url":"https:\/\/www.uni.lu\/fr","author_name":"UNI FR","author_url":"https:\/\/www.uni.lu\/fr","title":"Midbrain single-cell sequencing to understand Parkinson\u2019s Disease","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"uOPkNJDxul\"><a href=\"https:\/\/www.uni.lu\/fr\/news\/midbrain-single-cell-sequencing-to-understand-parkinsons-disease\/\">Midbrain single-cell sequencing to understand Parkinson\u2019s Disease<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/www.uni.lu\/fr\/news\/midbrain-single-cell-sequencing-to-understand-parkinsons-disease\/embed\/#?secret=uOPkNJDxul\" width=\"600\" height=\"338\" title=\"\u00ab\u00a0Midbrain single-cell sequencing to understand Parkinson\u2019s Disease\u00a0\u00bb &#8212; UNI FR\" data-secret=\"uOPkNJDxul\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script>\n\/*! This file is auto-generated *\/\n!function(c,d){\"use strict\";var e=!1,o=!1;if(d.querySelector)if(c.addEventListener)e=!0;if(c.wp=c.wp||{},c.wp.receiveEmbedMessage);else if(c.wp.receiveEmbedMessage=function(e){var t=e.data;if(!t);else if(!(t.secret||t.message||t.value));else if(\/[^a-zA-Z0-9]\/.test(t.secret));else{for(var r,s,a,i=d.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),n=d.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),o=new RegExp(\"^https?:$\",\"i\"),l=0;l<n.length;l++)n[l].style.display=\"none\";for(l=0;l<i.length;l++)if(r=i[l],e.source!==r.contentWindow);else{if(r.removeAttribute(\"style\"),\"height\"===t.message){if(1e3<(s=parseInt(t.value,10)))s=1e3;else if(~~s<200)s=200;r.height=s}if(\"link\"===t.message)if(s=d.createElement(\"a\"),a=d.createElement(\"a\"),s.href=r.getAttribute(\"src\"),a.href=t.value,!o.test(a.protocol));else if(a.host===s.host)if(d.activeElement===r)c.top.location.href=t.value}}},e)c.addEventListener(\"message\",c.wp.receiveEmbedMessage,!1),d.addEventListener(\"DOMContentLoaded\",t,!1),c.addEventListener(\"load\",t,!1);function t(){if(o);else{o=!0;for(var e,t,r,s=-1!==navigator.appVersion.indexOf(\"MSIE 10\"),a=!!navigator.userAgent.match(\/Trident.*rv:11\\.\/),i=d.querySelectorAll(\"iframe.wp-embedded-content\"),n=0;n<i.length;n++){if(!(r=(t=i[n]).getAttribute(\"data-secret\")))r=Math.random().toString(36).substr(2,10),t.src+=\"#?secret=\"+r,t.setAttribute(\"data-secret\",r);if(s||a)(e=t.cloneNode(!0)).removeAttribute(\"security\"),t.parentNode.replaceChild(e,t);t.contentWindow.postMessage({message:\"ready\",secret:r},\"*\")}}}}(window,document);\n<\/script>\n","description":"Researchers from the Luxembourg Centre for Systems Biomedicine (LCSB) at the University of Luxembourg, in collaboration with the Max Planck Institute for Molecular Genetics in Berlin, investigated the different cell types present in the human midbrain to better understand their respective role in Parkinson\u2019s disease.\u00a0\u00a0They examined post-mortem samples from people affected by the disease and from healthy individuals, and generated a unique single-nuclei RNA sequencing dataset. Their results, recently published in the scientific journal\u00a0Brain, revealed the existence of a specific cluster of cells in the midbrain of Parkinson\u2019s patients. They also highlighted the role of glial cells \u2013 the non-neuronal cells in the brain \u2013 in the pathology of this movement disorder.","thumbnail_url":"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/11\/2022\/03\/midbrain_single_cell_sequencing_to_understand_parkinson_s_disease.jpg","thumbnail_width":800,"thumbnail_height":600}