{"id":21049,"date":"2024-10-30T15:54:49","date_gmt":"2024-10-30T14:54:49","guid":{"rendered":"https:\/\/www.uni.lu\/fhse-en\/?post_type=research-groups&#038;p=21049"},"modified":"2026-01-14T11:42:24","modified_gmt":"2026-01-14T10:42:24","slug":"research","status":"publish","type":"research-groups","link":"https:\/\/www.uni.lu\/fhse-en\/research-groups\/p3\/research\/","title":{"rendered":"research"},"content":{"rendered":"<div class=\"section py-0 static\">\n<section class=\"py-0 wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\"><!-- SecondaryNavigationMirror --><div class=\"js-secondary-nav--sticky wp-block-unilux-blocks-secondary-navigation\" id=\"e6b6daf5-2857-4932-8831-ac1d72b6c3d9\">\n    <nav id=\"secondary-navigation\" role=\"navigation\" aria-label=\"Secondary menu\" class=\"secondary-nav\">\n        <button class=\"secondary-nav__button btn btn-solid--primary w-full\" aria-expanded=\"false\" aria-controls=\"secondary-navigation__list\" title=\"The selected page is Overview\" type=\"button\">\n            <span class=\"btn__name mr-auto\">Overview<\/span>\n            <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n                <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-down\" \/>\n            <\/svg>\n        <\/button>\n\n        <ul id=\"secondary-navigation__list\" class=\"secondary-nav__list\">\n            <li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/fhse-en\/research-groups\/p3\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Overview<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/fhse-en\/research-groups\/p3\/research\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Research<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/fhse-en\/research-groups\/p3\/people\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">People<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/fhse-en\/research-groups\/p3\/contact\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Contact<\/span>\n    <\/a>\n<\/li>\n        <\/ul>\n    <\/nav>\n<\/div>\n<!-- end SecondaryNavigationMirror -->\n\n<div class=\"wp-block-unilux-blocks-spacer is-spacer-size-md\"><\/div>\n\n\n<h1 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"our-research\"\n    >\nOur research<\/h1>\n\n\n\n<p>Pain is a highly personal experience, influenced strongly by all kinds of factors, including psychological factors such as stress, emotions, attention, and expectations. For example, a negative mood may exacerbate pain, whereas a good mood may alleviate pain. Likewise, worrying about pain may make it worse, while positive expectations may provide relief. These types of psychological pain modulation are mediated by dedicated pathways in the central nervous system, the so-called \u201cdescending pain control\u201d system. This system consists of a network of brain regions that can send signals down via the brainstem and spinal cord, to either facilitate or inhibit upcoming nociceptive signals.<\/p>\n\n\n\n<p>In the P3Lab, we study various aspects of psychological pain modulation by combining neuroimaging, psychophysiology and behavioural experiments. One major research theme is the identification of predictors of pain modulation capacity. We conduct studies to explore the role of individual differences in cognitive function, attitudes and physiology in determining the success of different types of pain modulation strategies. We also explore the influence of biological factors such as age and sex in influencing pain perception and modulation. And finally, we use brain imaging techniques, such as fMRI and EEG, to explore how the brain mediates different forms of psychological pain modulation.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><figure class=\"wp-block-dev4-reusable-blocks-image  object-fit--scale-down\">\n    \n<img decoding=\"async\" class=\"wp-block-image unilux-custom-image-block\"\n                alt=\"\"\n            src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2024\/10\/P38.png\"\n                srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2024\/10\/P38-300x280.png 300w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2024\/10\/P38-768x716.png 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2024\/10\/P38.png 1025w\"\n                style=\"object-position: 50.00% 50.00%; font-family: &quot;object-fit: scale-down; object-position: 50.00% 50.00%;&quot;; aspect-ratio: 16\/9; object-fit: scale-down; width: 100%;\"\n        loading=\"lazy\"\n\/>    <\/figure><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><figure class=\"wp-block-dev4-reusable-blocks-image  object-fit--scale-down\">\n    \n<img decoding=\"async\" class=\"wp-block-image unilux-custom-image-block\"\n                alt=\"\"\n            src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2024\/10\/P39.png\"\n                srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2024\/10\/P39-300x160.png 300w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2024\/10\/P39-768x409.png 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2024\/10\/P39.png 921w\"\n                style=\"object-position: 50.00% 50.00%; font-family: &quot;object-fit: scale-down; object-position: 50.00% 50.00%;&quot;; aspect-ratio: 16\/9; object-fit: scale-down; width: 100%;\"\n        loading=\"lazy\"\n\/>    <\/figure><\/div>\n<\/div>\n\n\n<div class=\"wp-block-unilux-blocks-spacer is-spacer-size-sm\"><\/div>\n\n\n<h3 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"our-projects\"\n    >\nOur projects<\/h3>\n\n\n\n<ul class=\"wp-block-unilux-blocks-research-project-card-list flex flex-wrap justify-center sm:justify-start -mx-16\"><li class=\" w-full px-16 sm:w-1\/2 lg:w-1\/3 wp-block-unilux-blocks-research-project-card\">\n    <div class=\"ulux-card card-research bg-theme\">\n        <div class=\"ulux-card__container\">\n            <div class=\"ulux-card__visual\">\n                <img decoding=\"async\" class=\"w-full\" src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2024\/07\/iStock-1770034104-300x169.jpg\" srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2024\/07\/iStock-1770034104-300x169.jpg 300w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2024\/07\/iStock-1770034104-1024x576.jpg 1024w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2024\/07\/iStock-1770034104-768x432.jpg 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2024\/07\/iStock-1770034104-1536x864.jpg 1536w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2024\/07\/iStock-1770034104-2048x1152.jpg 2048w\" sizes=\"(max-width: 300px) 100vw, 300px\" alt=\"\" \/>\n            <\/div>\n            <div class=\"ulux-card__body\">\n                <div class=\"ulux-card__topic break-words\">Life Sciences &amp; Medicine<\/div>\n                <h3 class=\"ulux-card__title break-words\">\n                    <a class=\"link-absolute\" href=\"https:\/\/www.uni.lu\/fhse-en\/research-projects\/quantitative-sensory-profiling-in-chronic-pain-patients-undergoing-high-frequency-spinal-cord-stimulation-therapy\/\" target=\"_blank\">\n                        QUASPRO &#8211; Quantitative sensory profiling in chronic pain patients undergoing high frequency spinal cord stimulation therapy                    <\/a>\n                <\/h3>\n                <a class=\"link-text ulux-card__link link-absolute\" href=\"https:\/\/www.uni.lu\/fhse-en\/research-projects\/quantitative-sensory-profiling-in-chronic-pain-patients-undergoing-high-frequency-spinal-cord-stimulation-therapy\/\" target=\"_blank\">\n                    <span class=\"link-text__name\">Learn more<\/span>\n                     <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--external-link icon--2xs\"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--external-link\"><\/use><\/svg>                <\/a>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/li>\n<\/ul>\n\n\n\n<ul class=\"ulux-list\">\n<li class=\"ulux-list-item\">Audacious Brain Cognition Data Embeddings (ABCDE)<\/li>\n\n\n\n<li class=\"ulux-list-item\">The influence of stress on the efficacy of transcutaneous electrical nerve stimulation (PLANOS)<\/li>\n\n\n\n<li class=\"ulux-list-item\">Age-related Changes in Human pain perception and modulation: Evidence from functional brain imaging (ACHE)<\/li>\n\n\n\n<li class=\"ulux-list-item\">Cognitive Modulation of Pain in Aging \u2013 Impact of Stress and Executive Functions \u2013 a Psychophysiological Approach (PAGES)<\/li>\n<\/ul>\n<\/div><\/section>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Pain is a highly personal experience, influenced strongly by all kinds of factors, including psychological factors such as stress, emotions, attention, and expectations. For example, a negative mood may exacerbate pain, whereas a good mood may alleviate pain. Likewise, worrying about pain may make it worse, while positive expectations may provide relief. These types of psychological pain modulation are mediated by dedicated pathways in the central nervous system, the so-called \u201cdescending pain control\u201d system. This system consists of a network of brain regions that can send signals down via the brainstem and spinal cord, to either facilitate or inhibit upcoming nociceptive signals.<\/p>\n","protected":false},"author":296,"featured_media":0,"parent":21020,"menu_order":0,"template":"","meta":{"featured_image_focal_point":[],"show_featured_caption":false,"ulux_newsletter_groups":"","uluxPostTitle":"P3 LAB","uluxPrePostTitle":"Research Group","_trash_the_other_posts":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false},"field-of-interest":[],"organisation":[],"authorship":[296],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.3 (Yoast SEO v22.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>research - P3 LAB - FHSE research group I University of Luxembourg<\/title>\n<meta name=\"description\" content=\"Pain is a highly personal experience, influenced strongly by all kinds of factors, including psychological factors such as stress, emotions, attention, and expectations. 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