{"id":2072,"date":"2023-09-08T15:54:05","date_gmt":"2023-09-08T13:54:05","guid":{"rendered":"https:\/\/www.uni.lu\/fhse-en\/blog\/research-groups\/stress-pain-and-gene-environment-interplay\/research\/"},"modified":"2025-06-18T15:05:32","modified_gmt":"2025-06-18T13:05:32","slug":"research","status":"publish","type":"research-groups","link":"https:\/\/www.uni.lu\/fhse-en\/research-groups\/stress-pain-and-gene-environment-interplay\/research\/","title":{"rendered":"Research"},"content":{"rendered":"<div class=\"section py-0 static\">\n<section class=\"py-0 wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\"><!-- SecondaryNavigationMirror --><div class=\"js-secondary-nav--sticky wp-block-unilux-blocks-secondary-navigation\" id=\"37059693-661f-42fa-bc1e-216d75ada983\">\n    <nav id=\"secondary-navigation\" role=\"navigation\" aria-label=\"Secondary menu\" class=\"secondary-nav\">\n        <button class=\"secondary-nav__button btn btn-solid--primary w-full\" aria-expanded=\"false\" aria-controls=\"secondary-navigation__list\" title=\"The selected page is Overview\" type=\"button\">\n            <span class=\"btn__name mr-auto\">Overview<\/span>\n            <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n                <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-down\" \/>\n            <\/svg>\n        <\/button>\n\n        <ul id=\"secondary-navigation__list\" class=\"secondary-nav__list\">\n            <li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/fhse-en\/research-groups\/stress-pain-and-gene-environment-interplay\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link \">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Overview<\/span>\n    <\/a>\n<\/li>\n<li class=\"secondary-nav__item\">\n    <a href=\"https:\/\/www.uni.lu\/fhse-en\/research-groups\/stress-pain-and-gene-environment-interplay\/research\/\" target=\"\" rel=\"noreferrer noopener\" class=\"secondary-nav__link isactived\" aria-current=\"page\">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--xs\">\n            <use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\" \/>\n        <\/svg>\n        <span class=\"secondary-nav__name\">Research<\/span>\n    <\/a>\n<\/li>\n        <\/ul>\n    <\/nav>\n<\/div>\n<!-- end SecondaryNavigationMirror --><\/div><\/section>\n\n\n\n<section class=\"wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\">\n<h1 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"research-at-the-stress-and-pain-group\"\n    >\nResearch at the Stress and Pain Group<\/h1>\n\n\n\n<p>In our research, we are adopting an interdiscplinary approach to tackle questions related to stress, pain, and mental health. Methods include the study of gene expression and epigenetics, as well as psychophysiology and neuroimaging of stress and pain. Our group runs two labs within EPSYLON, the Psychobiology of Pain Processing Lab (P3Lab) and the Biochemical and Molecular Genetics (BMG) Lab.<\/p>\n\n\n\n<ul class=\"wp-block-unilux-blocks-custom-buttons btn-list\"><li class=\"wp-block-unilux-blocks-custom-button\"    aria-disabled=\"true\"\n    >\n    <a\n        role=\"link\"\n        aria-disabled=\"true\"\n                target=\"_self\"\n        class=\"btn btn--secondary\"\n            >P3Lab<\/a>\n<\/li>\n\n\n<li class=\"wp-block-unilux-blocks-custom-button\"    aria-disabled=\"true\"\n    >\n    <a\n        role=\"link\"\n        aria-disabled=\"true\"\n                target=\"_self\"\n        class=\"btn btn--primary\"\n            >BMG<\/a>\n<\/li>\n<\/ul>\n<\/div><\/section>\n\n\n\n<section class=\"wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\"><div class=\"content-card content-card--right content-card__overlay--hidden wp-block-unilux-blocks-content-card\">\n    \n<h2 class=\"content-card__heading has-text-align-left wp-block-unilux-blocks-heading\"    >\nStress, Pain and Gene-Environment Interplay<\/h2>\n<div class=\"content-card__visual wp-block-unilux-blocks-content-card-visual-area\">\n    \n<section class=\"wp-block-unilux-blocks-image-video-wrapper\">\n    <figure class=\"wp-block-dev4-reusable-blocks-image  object-fit--cover\">\n    \n<img decoding=\"async\" class=\"wp-block-image unilux-custom-image-block\"\n                alt=\"02 Brain DNA\"\n            src=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2023\/09\/02_Brain_DNAgukbzn.jpeg\"\n                srcset=\"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2023\/09\/02_Brain_DNAgukbzn-300x225.jpeg 300w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2023\/09\/02_Brain_DNAgukbzn-1024x768.jpeg 1024w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2023\/09\/02_Brain_DNAgukbzn-768x576.jpeg 768w, https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/2\/2023\/09\/02_Brain_DNAgukbzn.jpeg 1200w\"\n                style=\"object-position: 50.00% 50.00%; font-family: &quot;object-fit: cover; object-position: 50.00% 50.00%;&quot;; aspect-ratio: 3\/2; object-fit: cover; width: 100%;\"\n        loading=\"lazy\"\n\/>    <\/figure><\/section>\n<div class=\"wp-block-unilux-blocks-wrapper content-card__overlay\">\n<a class=\"wp-block-unilux-blocks-button-highlight-rounded bottom-left\" \n    href=\"#\"\n    target=\"_self\"\n>\n    \n<span class=\"btn-highlight-rounded__name wp-block-unilux-blocks-plain-text\"><\/span>    <span class=\"icon-rounded\">\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right icon--lg\"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>    <\/span>\n<\/a><\/div>\n<\/div><div class=\"content-card__body  wp-block-unilux-blocks-content-card-free-area\">\n    \n<h3 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"our-two-lines-of-research\"\n    >\nOur two lines of research<\/h3>\n\n<div class=\"wp-block-columns is-layout-flex wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p>We are trying to understand the mechanisms that link stress exposure with disorder onset and maintenance. The experience of adversity in childhood is of particular relevance, as early-life stress not only causes immediate harm, but is associated with health problems across the life-span.<br>In our research on gene-environment interplay, we investigate alterations of bio-behavioral stress response systems, inflammatory stress-immune cross-talk, and sub-cellular processes, such as epigenetic modification or gene expression dynamics, to understand how psychosocial risk becomes biologically embedded.<br><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p>A further important line of research investigates the influence of stress and psychological factors on the development and maintenance of enhanced pain sensitivity. We study the psychological, neurobiological, psychophysiological and genetic mechanisms involved in stress and pain processing in healthy individuals and patients. One important method in this line of research is neuroimaging: we use both electroencephalography (EEG) and functional magnetic resonance imaging (fMRI).  <br> <br><\/p>\n<\/div>\n<\/div>\n<\/div><\/div><\/div><\/section>\n\n\n\n<section class=\"wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\">\n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"research-projects\"\n    >\nResearch projects<\/h2>\n\n\n<ul class=\"flex flex-wrap mt-24 -mx-16  wp-block-unilux-blocks-free-content-card\">\n    <li class=\"w-full sm:w-1\/2 lg:w-1\/3 px-16  wp-block-unilux-blocks-free-content-card-item\">\n    <div class=\"ulux-card card-project-related bg-theme\">\n        <div class=\"ulux-card__container card__container\">\n                        <div class=\"ulux-card__body wp-block-unilux-blocks-free-content-card-item-body\">\n    \n<span class=\"ulux-card__related wp-block-unilux-blocks-plain-text\">CHAMP<\/span>\n<h3 class=\"ulux-card__title has-text-align-left wp-block-unilux-blocks-heading\"        id=\"champ-childhood-adversity-and-mental-health-project\"\n    >\nCHAMP \u2013 Childhood Adversity and Mental Health Project<\/h3>\n<div class=\"ulux-card__link-wrapper card__link wp-block-unilux-blocks-simple-cta\">\n    <a\n        href=\"https:\/\/www.uni.lu\/fhse-en\/research-projects\/champ\/\"\n        title=\"Learn more\"\n        class=\"link-text link-text--icon ulux-card__link link-text link-absolute\"\n        target=\"\"\n    >\n        <span class=\"link-text__body\">\n            <span class=\"link-text__name\">Learn more<\/span>\n        <\/span>\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>    <\/a>\n<\/div>\n<\/div>        <\/div>\n    <\/div>\n<\/li><li class=\"w-full sm:w-1\/2 lg:w-1\/3 px-16  wp-block-unilux-blocks-free-content-card-item\">\n    <div class=\"ulux-card card-project-related bg-theme\">\n        <div class=\"ulux-card__container card__container\">\n                        <div class=\"ulux-card__body wp-block-unilux-blocks-free-content-card-item-body\">\n    \n<span class=\"ulux-card__related wp-block-unilux-blocks-plain-text\">Adverse childhood<\/span>\n<h3 class=\"ulux-card__title has-text-align-left wp-block-unilux-blocks-heading\"        id=\"adverse-childhood-experience-and-stress-regulation\"\n    >\nAdverse childhood experience and stress regulation<\/h3>\n<div class=\"ulux-card__link-wrapper card__link wp-block-unilux-blocks-simple-cta\">\n    <a\n        href=\"https:\/\/www.uni.lu\/fhse-en\/research-projects\/adverse-childhood-experience-and-stress-regulation\/\"\n        title=\"Learn more\"\n        class=\"link-text link-text--icon ulux-card__link link-text link-absolute\"\n        target=\"\"\n    >\n        <span class=\"link-text__body\">\n            <span class=\"link-text__name\">Learn more<\/span>\n        <\/span>\n        <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>    <\/a>\n<\/div>\n<\/div>        <\/div>\n    <\/div>\n<\/li><li class=\"w-full sm:w-1\/2 lg:w-1\/3 px-16  wp-block-unilux-blocks-free-content-card-item\">\n    <div class=\"ulux-card card-project-related bg-theme\">\n        <div class=\"ulux-card__container card__container\">\n                        <div class=\"ulux-card__body wp-block-unilux-blocks-free-content-card-item-body\">\n    \n<span class=\"ulux-card__related wp-block-unilux-blocks-plain-text\"><\/span>\n<h3 class=\"ulux-card__title has-text-align-left wp-block-unilux-blocks-heading\"    >\n<\/h3>\n<\/div>        <\/div>\n    <\/div>\n<\/li><\/ul>\n\n\n<ul class=\"wp-block-unilux-blocks-custom-buttons btn-list justify-center\"><li class=\"wp-block-unilux-blocks-custom-button\"    aria-disabled=\"false\"\n    >\n    <a\n        role=\"link\"\n        aria-disabled=\"false\"\n                    href=\"https:\/\/www.uni.lu\/research-en\/research-projects-overview\/?fq_research-projects-taxonomies-organisation%5B%5D=stress-pain-and-gene-environment-interplay%7CStress%2C+Pain%2C+and+Gene-Environment+Interplay%7COrganisation\"\n                target=\"_self\"\n        class=\"btn btn--primary\"\n            >All projects<\/a>\n<\/li>\n<\/ul>\n<\/div><\/section>\n\n\n\n<section class=\"wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\">\n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"projects\"\n    >\nSome of our projects<\/h2>\n\n\n\n<p>We are conducting a wide range of projects with healthy participants and patients, across all age groups. These include cross-sectional experimental studies, quasi-experimental longitudinal studies, and randomized controlled trials. In our research, we are collaborating with various national and international partners. <\/p>\n\n\n\n<div class=\"wp-block-unilux-blocks-accordion accordion accordion--theme accordion-standard\" data-reference=\"a748ad36-b04b-43b1-924a-45936887e2b7\" data-accordion-type=\"standard\"><div class=\"accordion__item  wp-block-unilux-blocks-accordion-item\">\n    <h3 class=\"accordion__header\"\n        >\n        <button\n            type=\"button\"\n            id=\"accordion-labelledby-20938236-bc9f-42da-8d42-14df5308917e\"\n            class=\"accordion__button collapsed\"\n            aria-expanded=\"false\"\n            aria-controls=\"accordion-panel-20938236-bc9f-42da-8d42-14df5308917e\"\n            data-bs-toggle=\"collapse\"\n            data-bs-target=\"#accordion-panel-20938236-bc9f-42da-8d42-14df5308917e\"\n        >\n            <span class=\"accordion__title\">\n                                The effects of childhood adversity on mental health and learning: A nationwide longitudinal project with children in alternative care in Luxembourg (CHAMP)            <\/span>\n\n            <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-down \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-down\"><\/use><\/svg>        <\/button>\n    <\/h3>\n    <div id=\"accordion-panel-20938236-bc9f-42da-8d42-14df5308917e\"\n        class=\"accordion__collapse collapse\"\n        aria-labelledby=\"accordion-labelledby-20938236-bc9f-42da-8d42-14df5308917e\"\n        data-bs-parent=\"[data-reference=&quot;a748ad36-b04b-43b1-924a-45936887e2b7&quot;]\"\n    >\n        <div class=\"accordion__body \">\n            \n<ul class=\"wp-block-unilux-blocks-highlighted-list list-highlighted list-highlighted--architectural\"><li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"start-date\"\n    >\nStart date<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>01\/09\/2023<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"duration-in-months\"\n    >\nDuration in months<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>48<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"funding\"\n    >\nFunding<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>FNR<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"project-team\"\n    >\nProject Team<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>Robert Kumsta; Pascale Engel De Abreu; Cyril Wealer; Jon Turner<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"partners\"\n    >\nPartners<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>Silvia Schneider, Ruhr-Universit\u00e4t Bochum; Office Nationale D\u2019Enfance, FEDAS<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"abstract\"\n    >\nAbstract<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>Children raised in alternative care have been separated from their parents and placed to live in an institutional home or in family-based foster care. Many of these children have experienced severe adversity and trauma in their homes, such as physical abuse or emotional maltreatment. Children raised in alternative care are a high-risk group for poor developmental outcomes. Far too many present mental health problems, learning and language difficulties, and poor educational results. Although children in alternative care are at higher risks of mental health and learning problems than children not in care, there is a dearth of data on these children\u2019s development and consequently their mental health and educational needs remain poorly understood. This study aims to determine how many children in the Luxembourg alternative care system present mental health problems and learning difficulties. Towards this end, the study will follow over 700 children and adolescents aged between 4 and 16 years growing up in different forms of alternative care. The study establishes basic prevalence rates of mental health and learning problems. The project also aims to discover which specific external and internal protective and risk factors are related to mental health and learning in children and adolescents in alternative care. The study will explore specific mechanisms by which early adversity and trauma may affect mental health and learning. Children will provide a DNA sample for epigenetic testing and they will complete tests of executive function. This is the first study in Luxembourg to collect these important data. It will generate essential findings that can inform policy and practice in Luxembourg. The study is also internationally relevant as it is among the first to explore relationships with a broad range of risk and protective factors including contextual and psychological factors as well as epigenetic alterations. <\/p>\n<\/div><\/div><\/li><\/ul>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div class=\"accordion__item  wp-block-unilux-blocks-accordion-item\">\n    <h3 class=\"accordion__header\"\n        >\n        <button\n            type=\"button\"\n            id=\"accordion-labelledby-c8994d84-6de5-4296-81f9-7d9f1a8dc6c0\"\n            class=\"accordion__button collapsed\"\n            aria-expanded=\"false\"\n            aria-controls=\"accordion-panel-c8994d84-6de5-4296-81f9-7d9f1a8dc6c0\"\n            data-bs-toggle=\"collapse\"\n            data-bs-target=\"#accordion-panel-c8994d84-6de5-4296-81f9-7d9f1a8dc6c0\"\n        >\n            <span class=\"accordion__title\">\n                                Cognitive Modulation of Pain in Aging &#8211; Impact of stress and Executive Functions            <\/span>\n\n            <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-down \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-down\"><\/use><\/svg>        <\/button>\n    <\/h3>\n    <div id=\"accordion-panel-c8994d84-6de5-4296-81f9-7d9f1a8dc6c0\"\n        class=\"accordion__collapse collapse\"\n        aria-labelledby=\"accordion-labelledby-c8994d84-6de5-4296-81f9-7d9f1a8dc6c0\"\n        data-bs-parent=\"[data-reference=&quot;a748ad36-b04b-43b1-924a-45936887e2b7&quot;]\"\n    >\n        <div class=\"accordion__body \">\n            \n<ul class=\"wp-block-unilux-blocks-highlighted-list list-highlighted list-highlighted--architectural\"><li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"start-date\"\n    >\nStart date<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>01\/09\/2021<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"duration-in-months\"\n    >\nDuration in months<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>30<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"funding\"\n    >\nFunding<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>FNR<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"project-team\"\n    >\nProject Team<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>Angelika Dierolf, Marian van der Meulen, Wolfgang Miltner, Claus V\u00f6gele, Andr\u00e9 Schulz<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"abstract\"\n    >\nAbstract<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>While pain is ubiquitous in all age groups, older adults are hit hardest, with an overproportional number of older adults suffering from acute and pain and its consequences. Concomitantly, the treatment for older adults is insufficient with a severe under- and mistreatment. In our aging society, this implies a severe and growing burden for our healthcare system and the society. Since pharmacological treatments are less suitable due to polypharmacy and age-related changes in drug metabolism, non-pharmacological interventions are a promising option in the pain management of older adults.<br>The aim of this research project is therefore to investigate how cognitive modulation of pain is altered in the older population and whether age-related cognitive decline and stress and relevant lifestyle factors influence this relationship. With a neurophysiological approach, the project focusses on three cognitive strategies of pain modulation in healthy young vs. older adults, i.e., distraction of pain, placebo analgesia and hypnotic analgesia. Moreover, influencing factors as chronic and acute stress, sleep quality and physical activity are taken into account. To gain a comprehensive insight on the underlying mechanisms of cognitive pain modulation in aging and its influencing factors, we will use EEG, peripheral psychophysiological, and endocrine measures. The understanding of age-related differences in cognitive pain modulation and its influencing factors has a direct impact on the therapeutic application by providing indications for age-specific adaptations and possible protecting factors.<br><\/p>\n<\/div><\/div><\/li><\/ul>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div class=\"accordion__item  wp-block-unilux-blocks-accordion-item\">\n    <h3 class=\"accordion__header\"\n        >\n        <button\n            type=\"button\"\n            id=\"accordion-labelledby-ee9f2326-9390-47a3-998d-91bce7bb9870\"\n            class=\"accordion__button collapsed\"\n            aria-expanded=\"false\"\n            aria-controls=\"accordion-panel-ee9f2326-9390-47a3-998d-91bce7bb9870\"\n            data-bs-toggle=\"collapse\"\n            data-bs-target=\"#accordion-panel-ee9f2326-9390-47a3-998d-91bce7bb9870\"\n        >\n            <span class=\"accordion__title\">\n                                Quantitative sensory profiling in chronic pain patients undergoing high-frequency spinal cord stimulation therapy            <\/span>\n\n            <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-down \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-down\"><\/use><\/svg>        <\/button>\n    <\/h3>\n    <div id=\"accordion-panel-ee9f2326-9390-47a3-998d-91bce7bb9870\"\n        class=\"accordion__collapse collapse\"\n        aria-labelledby=\"accordion-labelledby-ee9f2326-9390-47a3-998d-91bce7bb9870\"\n        data-bs-parent=\"[data-reference=&quot;a748ad36-b04b-43b1-924a-45936887e2b7&quot;]\"\n    >\n        <div class=\"accordion__body \">\n            \n<ul class=\"wp-block-unilux-blocks-highlighted-list list-highlighted list-highlighted--architectural\"><li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"start-date\"\n    >\nStart date<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>01\/01\/2019<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"duration-in-months\"\n    >\nDuration in months<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>72<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"funding\"\n    >\nFunding<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>Nevro Corp<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"project-team\"\n    >\nProject Team<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>Marian van der Meulen; Frank Hertel; Fernand Anton<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"partners\"\n    >\nPartners<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>Centre Hospitalier de Luxembourg<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"abstract\"\n    >\nAbstract<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>Electrical spinal cord stimulation (SCS) for the treatment of chronic pain has been used for decades. A recently introduced novel SCS protocol uses very high pulse frequencies and has been shown to be more effective than traditional SCS. The mechanism of action of this form of high frequency therapy (HF10) is still poorly understood. It is likely to involve spinal modulation as well as cerebral influences. In this study we address the mechanism of action of HF10 by establishing sensory profiles of patients. No previous studies have used quantitative sensory testing (QST) to prospectively investigate patients undergoing HF10 therapy. We study the functioning of somatosensory nerve fibres and of dynamic processes related to spinal cord plasticity and to activation of descending pain control pathways. Patients with chronic back and leg pain, as well as age-matched control subjects take part in the study. They undergo a QST battery at fixed time intervals (pre-treatment, during trial period, and at 1, 3, 6 and 12 months follow-up), and fill out questionnaires related to their pain experience and personality factors. <\/p>\n<\/div><\/div><\/li><\/ul>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div class=\"accordion__item  wp-block-unilux-blocks-accordion-item\">\n    <h3 class=\"accordion__header\"\n        >\n        <button\n            type=\"button\"\n            id=\"accordion-labelledby-f6b406df-ba15-4086-a626-a75703f0299d\"\n            class=\"accordion__button collapsed\"\n            aria-expanded=\"false\"\n            aria-controls=\"accordion-panel-f6b406df-ba15-4086-a626-a75703f0299d\"\n            data-bs-toggle=\"collapse\"\n            data-bs-target=\"#accordion-panel-f6b406df-ba15-4086-a626-a75703f0299d\"\n        >\n            <span class=\"accordion__title\">\n                                Stress in daily life &#8211; a gene-environment interaction study            <\/span>\n\n            <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-down \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-down\"><\/use><\/svg>        <\/button>\n    <\/h3>\n    <div id=\"accordion-panel-f6b406df-ba15-4086-a626-a75703f0299d\"\n        class=\"accordion__collapse collapse\"\n        aria-labelledby=\"accordion-labelledby-f6b406df-ba15-4086-a626-a75703f0299d\"\n        data-bs-parent=\"[data-reference=&quot;a748ad36-b04b-43b1-924a-45936887e2b7&quot;]\"\n    >\n        <div class=\"accordion__body \">\n            \n<ul class=\"wp-block-unilux-blocks-highlighted-list list-highlighted list-highlighted--architectural\"><li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"start-date\"\n    >\nStart date<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>01\/05\/2023<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"duration-in-months\"\n    >\nDuration in months<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>48<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"project-team\"\n    >\nProject Team<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>Mehves Kouris; Robert Kumsta<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"partners\"\n    >\nPartners<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>Maike Luhmann, Ruhr-University Bochum, Germany<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"abstract\"\n    >\nAbstract<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>Psychological stress comes in many flavors. One major source of stress comes from psychosocial influences we are confronted with in our daily life, such as interpersonal conflict, work-related stress, or loneliness. There is large heterogeneity in the way we deal with stress. Given that so-called micro stressors (or daily hassles) have been shown to predict onset and course of mental disorders, it is important to understand why and how people differ in their susceptibility to external events. The aim of this project is to thus to understand how the exposure to work-related stress, social stress and other daily hassles influence emotions and the change of emotions across the day using an Ecological Momentary Assessment design. We will also investigate the role of genetic variability in the association between stress exposure and changes in affect using polygenic scores for stress-related disorders as moderators.<\/p>\n<\/div><\/div><\/li><\/ul>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div class=\"accordion__item  wp-block-unilux-blocks-accordion-item\">\n    <h3 class=\"accordion__header\"\n        >\n        <button\n            type=\"button\"\n            id=\"accordion-labelledby-ffe95f8c-adab-4909-a743-9b4a3b644644\"\n            class=\"accordion__button collapsed\"\n            aria-expanded=\"false\"\n            aria-controls=\"accordion-panel-ffe95f8c-adab-4909-a743-9b4a3b644644\"\n            data-bs-toggle=\"collapse\"\n            data-bs-target=\"#accordion-panel-ffe95f8c-adab-4909-a743-9b4a3b644644\"\n        >\n            <span class=\"accordion__title\">\n                                Adverse childhood experience and stress regulation            <\/span>\n\n            <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-down \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-down\"><\/use><\/svg>        <\/button>\n    <\/h3>\n    <div id=\"accordion-panel-ffe95f8c-adab-4909-a743-9b4a3b644644\"\n        class=\"accordion__collapse collapse\"\n        aria-labelledby=\"accordion-labelledby-ffe95f8c-adab-4909-a743-9b4a3b644644\"\n        data-bs-parent=\"[data-reference=&quot;a748ad36-b04b-43b1-924a-45936887e2b7&quot;]\"\n    >\n        <div class=\"accordion__body \">\n            \n<ul class=\"wp-block-unilux-blocks-highlighted-list list-highlighted list-highlighted--architectural\"><li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"start-date\"\n    >\nStart date<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>01\/05\/2019<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"duration-in-months\"\n    >\nDuration in months<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>48<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"funding\"\n    >\nFunding<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>DFG<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"project-team\"\n    >\nProject Team<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>Robert Kumsta<\/p>\n<\/div><\/div><\/li>\n\n<li class=\"list-highlighted__item  wp-block-unilux-blocks-highlighted-list-item\">\n    <header class=\"list-highlighted__header wp-block-unilux-blocks-highlighted-list-item-header\">\n    \n<h5 class=\"text-18 has-text-align-left wp-block-unilux-blocks-heading\"        id=\"abstract\"\n    >\nAbstract<\/h5>\n<div class=\"wp-block-unilux-blocks-bigtext\">\n    <span>\n        \n    <\/span>\n<\/div><\/header><div class=\"list-highlighted__body wp-block-unilux-blocks-highlighted-list-item-body\">\n    <div class=\"wp-block-unilux-blocks-highlighted-list-item-free-content-area\">\n    \n<p>This project focussed on the molecular and genetic mechanisms underlying the effects of early life stress and adversity on physical and mental health outcomes in later life. <br>We demonstrated that individuals with a history of childhood adversity exhibited altered hormonal and gene expression in response to stress, particularly in genes involved in the regulation of inflammation and immune response. Furthermore, utilising a proteomics approach, we found that the experience of adversity in  childhood was associated with changes in the expression of proteins related to mitochondrial function, suggesting a potential link between early-life stress and mitochondrial dysfunction.<\/p>\n<\/div><\/div><\/li><\/ul>\n        <\/div>\n    <\/div>\n<\/div><\/div>\n<\/div><\/section>\n\n\n<section class=\"section section wp-block-unilux-blocks-quick-link-discover-section\">\n    <div class=\"container xl:max-w-screen-xl\">\n        \n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"discover-more\"\n    >\nDiscover more<\/h2>\n\n<ul class=\"wp-block-unilux-blocks-quick-link-discover quick-link-list\">\n<li class=\"wp-block-unilux-blocks-quick-link-discover-item\">\n    <a\n                    href=\"https:\/\/www.hopitauxschuman.lu\/fr\/specialites-maladies-traitements\/imagerie-medicale-radiologie\/\"\n                    class=\"quick-link\"\n            target=\"_blank\"\n    >\n            <span class=\"quick-link__container\">\n                <span class=\"quick-link__text\">\n                    Radiology Zitha (HRS)                <\/span>\n                <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--external-link \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--external-link\"><\/use><\/svg>            <\/span>\n    <\/a>\n<\/li>\n\n\n\n<li class=\"wp-block-unilux-blocks-quick-link-discover-item\">\n    <a\n                    class=\"quick-link\"\n            target=\"_blank\"\n    >\n            <span class=\"quick-link__container\">\n                <span class=\"quick-link__text\">\n                    Genetic Psychology (coming soon)                <\/span>\n                <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--external-link \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--external-link\"><\/use><\/svg>            <\/span>\n    <\/a>\n<\/li>\n\n\n\n<li class=\"wp-block-unilux-blocks-quick-link-discover-item\">\n    <a\n                    href=\"https:\/\/www.uni.lu\/fhse-en\/epsylon\/\"\n                    class=\"quick-link\"\n            target=\"\"\n    >\n            <span class=\"quick-link__container\">\n                <span class=\"quick-link__text\">\n                    EPSYLON                <\/span>\n                <svg aria-hidden=\"true\" focusable=\"false\" class=\"icon icon-outline icon--arrow-right \"><use xlink:href=\"https:\/\/www.uni.lu\/wp-content\/themes\/unilux-theme\/assets\/images\/icons\/icons-outline.svg#icon--arrow-right\"><\/use><\/svg>            <\/span>\n    <\/a>\n<\/li>\n<\/ul>\n    <\/div>\n<\/section><\/div>","protected":false},"excerpt":{"rendered":"<p>In our research, we are adopting an interdiscplinary approach to tackle questions related to stress, pain, and mental health. Methods include the study of gene expression and epigenetics, as well as psychophysiology and neuroimaging of stress and pain. Our group runs two labs within EPSYLON, the Psychobiology of Pain Processing Lab (P3Lab) and the Biochemical and Molecular Genetics (BMG) Lab.<\/p>\n","protected":false},"author":109,"featured_media":2070,"parent":2071,"menu_order":0,"template":"","meta":{"featured_image_focal_point":[],"show_featured_caption":false,"ulux_newsletter_groups":"","uluxPostTitle":"Stress, Pain, and Gene-Environment Interplay","uluxPrePostTitle":"Research Group","_trash_the_other_posts":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false},"field-of-interest":[],"organisation":[],"authorship":[109,107,111,296,391],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.3 (Yoast SEO v22.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Research - Stress, Pain, and Gene-Environment Interplay - FHSE research group I University of Luxembourg<\/title>\n<meta name=\"description\" content=\"In our research, we are adopting an interdiscplinary approach to tackle questions related to stress, pain, and mental health. 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