{"id":7541,"date":"2019-01-15T14:31:27","date_gmt":"2019-01-15T14:31:27","guid":{"rendered":"https:\/\/website.prod.unilu.spikeseed.cloud\/en\/news\/prize-worthy-cross-border-diagnosis-research-for-parkinsons-patients\/"},"modified":"2019-01-15T14:31:27","modified_gmt":"2019-01-15T14:31:27","slug":"prize-worthy-cross-border-diagnosis-research-for-parkinsons-patients","status":"publish","type":"news","link":"https:\/\/www.uni.lu\/en\/news\/prize-worthy-cross-border-diagnosis-research-for-parkinsons-patients\/","title":{"rendered":"Prize-worthy: cross-border diagnosis research for Parkinson\u2019s patients"},"content":{"rendered":"<section class=\"wp-block-unilux-blocks-free-section section\"><div class=\"container xl:max-w-screen-xl\"><p>A German-Luxembourgish team of researchers from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg and the University of Saarland today received the second prize in the competition \u201cExcellent Networks in the Greater Region\u201d. The jury of the Interregional Science Prize bestowed this honour to their project which uses so-called biomarkers to create new approaches for early detection of Parkinson\u2019s disease.<\/p>\n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"interregional-research-prize\"\n    >\nInterregional research prize<\/h2>\n<p>The prize is worth 10,000 euros, donated by <a href=\"https:\/\/www.saarlb.de\/index.php?id=454\" target=\"_blank\" title=\"SaarLB\" rel=\"noopener\">SaarLB<\/a>. \u201cWe are honoured at this special acknowledgement of our work,\u201d says Prof. <a href=\"https:\/\/wwwen.uni.lu\/lcsb\/people\/rejko_krueger\" target=\"_self\" title=\"\" rel=\"noopener\">Rejko Kr\u00fcger<\/a>, head of the <a href=\"https:\/\/wwwen.uni.lu\/lcsb\/research\/translational_neuroscience\" target=\"_self\" title=\"\" rel=\"noopener\">Clinical &#038; Experimental Neuroscience Group<\/a> at <a href=\"https:\/\/wwwen.uni.lu\/centres\/luxembourg_centre_for_systems_biomedicine\" target=\"_self\" title=\"\" rel=\"noopener\">LCSB<\/a> and one of the distinguished researchers. \u201cFor one thing, it provides strong support for our work. But the prize can also make people in the Greater Region aware of the real medical advancements we are making for the patients, here and across national borders.\u201d<\/p><p>The Interregional Science Prize was first offered in 2003 with the aim of reinforcing scientific cooperation and networking as well as the profile of the scientific region of Saar, Lothringia, Luxembourg, Rhineland Palatinate, Wallonia and the French\/German-speaking community of Belgium, both internally and externally. It is awarded every two years during the Conference of Ministers of the Greater Region.<\/p>\n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"bringing-together-clinical-research-and-bioinformatics\"\n    >\nBringing together clinical research and bioinformatics<\/h2>\n<p>The award-winning research project brings together the specialised scientific knowledge of various research disciplines held in different regions that, only when combined, will be of true benefit for making medical breakthroughs. Rejko Kr\u00fcger heads the team leading the <a href=\"http:\/\/www.parkinson.lu\/\" target=\"_blank\" title=\"NCER-PD programme\" rel=\"noopener\">Luxembourg Parkinson\u2019s study \u201cNCER-PD\u201d<\/a>, in which scientists of <a href=\"https:\/\/wwwen.uni.lu\/lcsb\" target=\"_self\" title=\"\" rel=\"noopener\">LCSB<\/a>, the <a href=\"https:\/\/www.lih.lu\/\" target=\"_blank\" title=\"Luxembourg Institute of Health (LIH)\" rel=\"noopener\">Luxemburg Institute of Health<\/a> (LIH), the <a href=\"https:\/\/www.chl.lu\/\" target=\"_blank\" title=\"CHL\" rel=\"noopener\">Centre Hospitalier de Luxembourg<\/a> (CHL), the <a href=\"https:\/\/www.ibbl.lu\/\" target=\"_blank\" title=\"Integrated BioBank of Luxembourg (IBBL)\" rel=\"noopener\">Integrated Biobank of Luxembourg<\/a> (IBBL) and the <a href=\"https:\/\/lns.lu\/\" target=\"_blank\" title=\"LNS\" rel=\"noopener\">Laboratoire National de Sant\u00e9<\/a> (LNS) are involved. NCER-PD collects and analyses tissue samples and data from Parkinson\u2019s patients as well as samples from healthy control people for comparison. The aim is to improve the early detection of Parkinson\u2019s and the treatment of those afflicted.<\/p><p>The Saarland partner, sharing the award, is the team led by Prof. Andreas Keller. Keller is the head of the \u201cClinical Informatics\u201d workgroup in the Medical Faculty of the <a href=\"https:\/\/www.uni-saarland.de\/nc\/en\/home.html\" target=\"_blank\" title=\"Universit\u00e9 de la Sarre\" rel=\"noopener\">University of Saarland<\/a>. He intends to use molecules present in blood as biomarkers for diagnosing diseases in the earliest possible stages. \u201cMicro-RNAs are highly suitable for this,\u201d says Keller: \u201cThey are short segments of specific molecules that play an important role in controlling genes.\u201d<\/p>\n<h2 class=\"has-text-align-left wp-block-unilux-blocks-heading\"        id=\"use-of-biomarkers-for-early-diagnosis\"\n    >\nUse of biomarkers for early diagnosis<\/h2>\n<p>The percentages of different micro-RNAs found in the blood depend on a person\u2019s state of health. The researchers of LCSB have a very precise understanding of the latter in relation to the development of Parkinson\u2019s disease. \u201cAt the annual check-up which is part of the study, we take regular blood samples from our patients that can also be tested for their micro-RNA content,\u201d Kr\u00fcger explains. \u201cSo far, however, we have never had any biomarkers that can tell us about the stage of the disease.\u201d<\/p><p>This is where Keller\u2019s expertise comes in: \u201cAs clinical bioinformaticians, we have already developed special algorithms for other diseases, such as cancer. We can use these to identify, out of the total content, those micro-RNAs that indicate the onset of the disease with certainty \u2013 and can therefore be of diagnostic importance.\u201d<\/p><p>It is precisely this approach that they have now translated to Parkinson\u2019s disease in the scope of the German-Luxembourg cooperation \u2013 and can present their first successes, as Andreas Keller relates: \u201cWe have already identified a number of promising micro-RNAs on the computer. Further calculations will continue to narrow the circle down to those potential molecules that can actually be used as biomarkers in future clinical diagnoses. The related papers will be published soon.\u201d<\/p><p>\u201cWe are pleased that our new interdisciplinary approach to the development of biomarkers for early diagnosis of Parkinson\u2019s disease and the feasibility we have demonstrated have been honoured with the Interregional Science Prize,\u201d Rejko Kr\u00fcger declares. \u201cWe will now continue working intensively to ensure that our research benefits the people as quickly as possible in hospitals and medical practices.\u201d<\/p><p>\u00a9 University of Luxembourg<\/p><\/div><\/section>","protected":false},"excerpt":{"rendered":"<p>A German-Luxembourgish team of researchers from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg and the University of Saarland today received the second prize in the competition \u201cExcellent Networks in the Greater Region\u201d. The jury of the Interregional Science Prize bestowed this honour to their project which uses so-called biomarkers to create new approaches for early detection of Parkinson\u2019s disease.<\/p>\n","protected":false},"author":0,"featured_media":7542,"template":"","format":"standard","meta":{"featured_image_focal_point":[],"show_featured_caption":false,"ulux_newsletter_groups":"","uluxPostTitle":"","uluxPrePostTitle":"","_trash_the_other_posts":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false},"news-category":[11,10],"news-topic":[26],"organisation":[209,227,233],"authorship":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.3 (Yoast SEO v22.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Prize-worthy: cross-border diagnosis research for Parkinson\u2019s patients - University of Luxembourg<\/title>\n<meta name=\"description\" content=\"A German-Luxembourgish team of researchers from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg and the University of Saarland today received the second prize in the competition \u201cExcellent Networks in the Greater Region\u201d. 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