{"version":"1.0","provider_name":"UNI EN","provider_url":"https:\/\/www.uni.lu\/en","author_name":"UNI EN","author_url":"https:\/\/www.uni.lu\/en","title":"PathoFact identifies pathogens faster and more accurately","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"UaNHs9aVt5\"><a href=\"https:\/\/www.uni.lu\/en\/news\/pathofact-identifies-pathogens-faster-and-more-accurately\/\">PathoFact identifies pathogens faster and more accurately<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/www.uni.lu\/en\/news\/pathofact-identifies-pathogens-faster-and-more-accurately\/embed\/#?secret=UaNHs9aVt5\" width=\"600\" height=\"338\" title=\"&#8220;PathoFact identifies pathogens faster and more accurately&#8221; &#8212; UNI EN\" data-secret=\"UaNHs9aVt5\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script>\n\/*! This file is auto-generated *\/\n!function(c,d){\"use strict\";var e=!1,o=!1;if(d.querySelector)if(c.addEventListener)e=!0;if(c.wp=c.wp||{},c.wp.receiveEmbedMessage);else if(c.wp.receiveEmbedMessage=function(e){var t=e.data;if(!t);else if(!(t.secret||t.message||t.value));else if(\/[^a-zA-Z0-9]\/.test(t.secret));else{for(var r,s,a,i=d.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),n=d.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),o=new RegExp(\"^https?:$\",\"i\"),l=0;l<n.length;l++)n[l].style.display=\"none\";for(l=0;l<i.length;l++)if(r=i[l],e.source!==r.contentWindow);else{if(r.removeAttribute(\"style\"),\"height\"===t.message){if(1e3<(s=parseInt(t.value,10)))s=1e3;else if(~~s<200)s=200;r.height=s}if(\"link\"===t.message)if(s=d.createElement(\"a\"),a=d.createElement(\"a\"),s.href=r.getAttribute(\"src\"),a.href=t.value,!o.test(a.protocol));else if(a.host===s.host)if(d.activeElement===r)c.top.location.href=t.value}}},e)c.addEventListener(\"message\",c.wp.receiveEmbedMessage,!1),d.addEventListener(\"DOMContentLoaded\",t,!1),c.addEventListener(\"load\",t,!1);function t(){if(o);else{o=!0;for(var e,t,r,s=-1!==navigator.appVersion.indexOf(\"MSIE 10\"),a=!!navigator.userAgent.match(\/Trident.*rv:11\\.\/),i=d.querySelectorAll(\"iframe.wp-embedded-content\"),n=0;n<i.length;n++){if(!(r=(t=i[n]).getAttribute(\"data-secret\")))r=Math.random().toString(36).substr(2,10),t.src+=\"#?secret=\"+r,t.setAttribute(\"data-secret\",r);if(s||a)(e=t.cloneNode(!0)).removeAttribute(\"security\"),t.parentNode.replaceChild(e,t);t.contentWindow.postMessage({message:\"ready\",secret:r},\"*\")}}}}(window,document);\n<\/script>\n","thumbnail_url":"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/9\/2021\/02\/pathofact_identifie_les_agents_pathogenes_plus_vite_et_precisement.jpg","thumbnail_width":800,"thumbnail_height":600,"description":"Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) and the Department of Life Sciences and Medicine of the University of Luxembourg have developed a new bioinformatics tool that can help them identify pathogens much faster and more accurately than was ever possible with conventional diagnostic methods. The team led by Professor Paul Wilmes, head of the Systems Ecology group at the LCSB, makes use of so-called metagenomic data. Using high-throughput methods, they sequence all of the genome fragments obtained from samples that potentially contain pathogenic organisms. The new bioinformatics tool \u2013 which the LCSB team has named PathoFact \u2013 compares these gene sequences against an integrated database. PathoFact identifies the genes of microorganisms that are responsible for their pathogenic potential or \u2013 in the case of bacteria \u2013 their antibiotic resistance. Based on this knowledge, the researchers can determine which pathogens are responsible for an infection and, in future clinical practice, suggest suitable treatments. PathoFact furthermore helps scientists to better understand the influence of microorganisms in the onset of chronic diseases such as Parkinson\u2019s or rheumatoid arthritis."}