{"version":"1.0","provider_name":"UNI EN","provider_url":"https:\/\/www.uni.lu\/en","author_name":"valentinadelgaudio","author_url":"https:\/\/www.uni.lu\/en\/author\/valentinadelgaudio\/","title":"How damaged cells inhibit muscle regeneration over lifetime","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"VWUp86b95g\"><a href=\"https:\/\/www.uni.lu\/en\/news\/how-damaged-cells-inhibit-muscle-regeneration-over-lifetime\/\">How damaged cells inhibit muscle regeneration over lifetime<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/www.uni.lu\/en\/news\/how-damaged-cells-inhibit-muscle-regeneration-over-lifetime\/embed\/#?secret=VWUp86b95g\" width=\"600\" height=\"338\" title=\"&#8220;How damaged cells inhibit muscle regeneration over lifetime&#8221; &#8212; UNI EN\" data-secret=\"VWUp86b95g\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script>\n\/*! This file is auto-generated *\/\n!function(c,d){\"use strict\";var e=!1,o=!1;if(d.querySelector)if(c.addEventListener)e=!0;if(c.wp=c.wp||{},c.wp.receiveEmbedMessage);else if(c.wp.receiveEmbedMessage=function(e){var t=e.data;if(!t);else if(!(t.secret||t.message||t.value));else if(\/[^a-zA-Z0-9]\/.test(t.secret));else{for(var r,s,a,i=d.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),n=d.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),o=new RegExp(\"^https?:$\",\"i\"),l=0;l<n.length;l++)n[l].style.display=\"none\";for(l=0;l<i.length;l++)if(r=i[l],e.source!==r.contentWindow);else{if(r.removeAttribute(\"style\"),\"height\"===t.message){if(1e3<(s=parseInt(t.value,10)))s=1e3;else if(~~s<200)s=200;r.height=s}if(\"link\"===t.message)if(s=d.createElement(\"a\"),a=d.createElement(\"a\"),s.href=r.getAttribute(\"src\"),a.href=t.value,!o.test(a.protocol));else if(a.host===s.host)if(d.activeElement===r)c.top.location.href=t.value}}},e)c.addEventListener(\"message\",c.wp.receiveEmbedMessage,!1),d.addEventListener(\"DOMContentLoaded\",t,!1),c.addEventListener(\"load\",t,!1);function t(){if(o);else{o=!0;for(var e,t,r,s=-1!==navigator.appVersion.indexOf(\"MSIE 10\"),a=!!navigator.userAgent.match(\/Trident.*rv:11\\.\/),i=d.querySelectorAll(\"iframe.wp-embedded-content\"),n=0;n<i.length;n++){if(!(r=(t=i[n]).getAttribute(\"data-secret\")))r=Math.random().toString(36).substr(2,10),t.src+=\"#?secret=\"+r,t.setAttribute(\"data-secret\",r);if(s||a)(e=t.cloneNode(!0)).removeAttribute(\"security\"),t.parentNode.replaceChild(e,t);t.contentWindow.postMessage({message:\"ready\",secret:r},\"*\")}}}}(window,document);\n<\/script>\n","thumbnail_url":"https:\/\/www.uni.lu\/wp-content\/uploads\/sites\/9\/2023\/11\/Placeholder_news.png","thumbnail_width":1500,"thumbnail_height":1125,"description":"Humans have a limited capacity for self-regeneration of tissues and organs but they do keep a pool of stem cells throughout their life that can self-renew and differentiate into specific cell types. These stem cells are widely studied as they could enable the repair of human tissues and thus have great potential for medicine. On the other hand, all human cells can enter a state called senescence: they stop multiplying but don\u2019t die, lingering within the tissue. As these senescent cells accumulate throughout the body, they can impact nearby healthy cells. An international team of researchers, including Prof. Antonio Del Sol from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg and from CIC bioGUNE-BRTA, recently explored the role of senescent cells in tissue regeneration. They uncovered key interactions between senescent cells and stem cells, opening potential avenues towards improving muscle repair throughout life. Their findings are published in Nature in December."}